New research progress on 363-72-4 in 2021.Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction by binding to a specific portion of an enzyme and thus slowing or preventing a reaction from occurring. 363-72-4, Name is Pentafluorobenzene, molecular formula is , belongs to benzoxazole compound. In a document, author is Singh, Varinder, Recommanded Product: 363-72-4.
A novel series of benzoxazolyl linked benzylidene based rhodanine and their cyclic analogs were synthesized, characterized and evaluated for their alpha-amyloglucosidase inhibitory activity. Out of eight target compounds, two compounds (4b and 5b) displayed potent inhibitory activity against alpha-amyloglucosidase with IC50 values in the range of 0.24 +/- 0.01-0.94 +/- 0.01 A mu M as compared to standard drug acarbose. Among all the tested compounds, compound 5b containing rhodanine at 3-position of phenyl was found to be the most active inhibitor of alpha-amyloglucosidase. Docking studies showed the existence of potential H-bonding interactions between synthesized compounds and alpha-glucosidase which might be responsible for good biological activity.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 363-72-4. Recommanded Product: 363-72-4.
Reference:
Benzoxazole – Wikipedia,
,Benzoxazole | C7H5NO – PubChem