Reference of 3621-81-6, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.3621-81-6, Name is 2,5-Dichlorobenzooxazole, molecular formula is C7H3Cl2NO. In a article£¬once mentioned of 3621-81-6
Benzoxazole piperidines as selective and potent somatostatin receptor subtype 5 antagonists
SAR studies of a recently described SST5R selective benzoxazole piperidine lead series are described with particular focus on the substitution pattern on the benzyl and benzoxazole side-chains. Introduction of a second meta substituent at the benzyl unit significantly lowers residual hH1 activity and insertion of substituents onto the benzoxazole periphery entirely removes remaining h5-HT2B activity. Compounds with single digit nM activity, functional antagonism and favorable physicochemical properties endowed with a good pharmacokinetic profile in rats are described which should become valuable tools for exploring the pharmacological role of the SST5 receptor in vivo.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 3621-81-6
Reference£º
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem