In an article, author is Wang, Kezhou, once mentioned the application of 6825-20-3, Product Details of 6825-20-3, Name is 3,6-Dibromo-9H-carbazole, molecular formula is C12H7Br2N, molecular weight is 325, MDL number is MFCD00004961, category is benzoxazole. Now introduce a scientific discovery about this category.
Enantioselective Reaction between 2-(Cyanomethyl)azaarenes and N-Boc-amino Sulfones
A series of 2-(cyanomethyl)azaarenes containing benzothiazole or benzoxazole were designed and synthesized for asymmetric alpha-functionalization with N-Boc-amino sulfones. The Mannich adducts were obtained in high yields with good diastereo- and enantioselectivities. Aryl substituted amino sulfones were tolerated under the current conditions, and the reaction can be performed on gram scale in good results.
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Reference:
Benzoxazole – Wikipedia,
,Benzoxazole | C7H5NO – PubChem