Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , Safety of Lithium difluoro(oxalato)borate, 409071-16-5, Name is Lithium difluoro(oxalato)borate, molecular formula is C2BF2LiO4, belongs to benzoxazole compound. In a document, author is Ravikumar, P., introduce the new discover.
Design, Synthesis, and Anticancer Evaluation of Tetrazole-Fused Benzoxazole Derivatives as Tubulin Binding Agents
A novel series of tetrazole fused benzoxazole derivatives 9a-9j are synthesized, and their structures are characterized by H-1 and C-13 NMR, and mass spectra. The compounds 9a, 9b, 9g, 9h, and 9j demonstrate the highest activity. The compounds 9b and 9g exhibit good anticancer activity, in particular against MCF7, Hop62, and A-549 cell lines with the range of GI(50) values from <0.1 to 4.56 M. Molecular docking study is carried out for the compounds 9a-9j, according to which the compound 9b forms one hydrogen bond with THR766 with the highest docking score (-7.33). This indicates that 9b is effeciently binging to tubulin site. A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 409071-16-5. Safety of Lithium difluoro(oxalato)borate.
Reference:
Benzoxazole – Wikipedia,
,Benzoxazole | C7H5NO – PubChem