Category: 2382-96-9

Benzo[d]oxazole-2-thiol, cas is 2382-96-9, it is a common heterocyclic compound, the benzoxazole compound, its synthesis route is as follows.,2382-96-9

General procedure: Typically, thiol (1 mmol), H2O2 (0.5 mL) and 0.005 g of catalystwas mixed with stirring. Upon completion of the reaction (monitoredby TLC), the catalyst was collected by simple filtration andthe resulting product was extracted, washed and the solvent evaporatedover anhydrous Na2SO4 (Scheme 1a).

As the rapid development of chemical substances, we look forward to future research findings about 2382-96-9

Reference£º
Article; Molaei, Somayeh; Tamoradi, Taiebeh; Ghadermazi, Mohammad; Ghorbani-Choghamarani, Arash; Polyhedron; vol. 156; (2018); p. 35 – 47;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem

As a common heterocyclic compound, it belong benzoxazole compound,Benzo[d]oxazole-2-thiol,2382-96-9,Molecular formula: C7H5NOS,mainly used in chemical industry, its synthesis route is as follows.,2382-96-9

General procedure: A sealed tube (90 mL) equipped with a magnetic stirring bar and an O2 balloon was charged with dichloroethane (DCE, 20 mL), thiophenol (1a, 4 mmol, 0.44 g) and TBN (0.16 mmol, 4 mol%, 19.2 mL). Then the tube was placed in an oil bath, which was preheated to 50C. The mixture was stirred for 1 h until starting material was completely consumed as monitored by GC and TLC. After removing the solvent, the residue was purified by column chromatography on silica gel to give the desired diphenyl disulfide (2a, 90%, 0.394 g) as a white solid.

With the synthetic route has been constantly updated, we look forward to future research findings about Benzo[d]oxazole-2-thiol,belong benzoxazole compound

Reference£º
Article; Yi, Shan-Li; Li, Mei-Chao; Hu, Xin-Quan; Mo, Wei-Min; Shen, Zhen-Lu; Chinese Chemical Letters; vol. 27; 9; (2016); p. 1505 – 1508;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem

As a common heterocyclic compound, it belongs to quinuclidine compound,Quinuclidine-4-carboxylic acid hydrochloride,40117-63-3,Molecular formula: C8H14ClNO118,mainly used in chemical industry, its synthesis route is as follows.,2382-96-9

To an oven dried flask equipped with a stir bar cooled under argon was added benzo[d]oxazole- 2(3H)-thione (0.375 grams, 2.48 mmol) and K2C03 (1.37, 9.92 mmol). The was taken up in 20.0 mL anhydrous acetone. After stirring for approximately minutes at room temperature, methyl iodide (0.25 mL, 3.97 mmol) was added. The solution continued to stir at room temperature overnight. The next day the solution was filtered through a plug of celite, and rinsed with dichloromethane and ethyl acetate. The solution was then concentrated. It was then taken up in ethyl acetate, filtered, and concentrated again. It was then used without further purification. Calculated mass for Chemical Formula: C8H7NOS Exact Mass: 165.02 observed 166.1 (M+l, MM API/ESI).

With the complex challenges of chemical substances, we look forward to future research findings about Benzo[d]oxazole-2-thiol,belong benzoxazole compound

Reference£º
Patent; MUSC FOUNDATION FOR RESEARCH DEVELOPMENT; U.S. DEPARTMENT OF VETERANS AFFAIRS; LINDSEY, Christopher, C.; BEESON, Craig, C.; SCHNELLMANN, Rick, G.; (51 pag.)WO2018/85491; (2018); A1;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem

2382-96-9, Benzo[d]oxazole-2-thiol is a benzoxazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: The substituted 2-aminophenol (1eq.) in water and 95% ethanol was added potassium carbonate (1eq.) and CS2 (1eq.).The mixture was heated under reflux for 3 hours. After cooling, the solution was neutralized with 15 mL of acetic acid in 30 mL water. The precipitate was collected to give 2-thiolbenzoxazoles. Then, the substituted 2-thiolbenzoxazoles (1eq.) dissolved in toluene, PCl5 (1.5eq) was added dropwise. The mixture was heated to reflux for 2 hours. After the solvent was evaporated, the crude product was purified by silica gel column chromatography using PE-EA as an eluent., 2382-96-9

2382-96-9 Benzo[d]oxazole-2-thiol 712377, abenzoxazole compound, is more and more widely used in various fields.

Reference£º
Article; Ouyang, Liang; Huang, Yuhui; Zhao, Yuwei; He, Gu; Xie, Yongmei; Liu, Jie; He, Jun; Liu, Bo; Wei, Yuquan; Bioorganic and Medicinal Chemistry Letters; vol. 22; 9; (2012); p. 3044 – 3049;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem

Benzo[d]oxazole-2-thiol, cas is 2382-96-9, it is a common heterocyclic compound, the benzoxazole compound, its synthesis route is as follows.,2382-96-9

General procedure: Thiols ((1 mmol), 5 mmol UHP, and 4 mL acetone as solvent along with 25 mg catalyst were added to a 10-mL two-necked flask equipped with a stirrer. The progress of the reaction was monitored by TLC. After completion of the reaction, the catalyst was removed and the pure products were extracted with CH2Cl2(3 9 10 mL). The results are presented in Table 6.

With the rapid development of chemical substances, we look forward to future research findings about Benzo[d]oxazole-2-thiol

Reference£º
Article; Nikoorazm, Mohsen; Ghorbani-Choghamarani, Arash; Noori, Nourolah; Research on Chemical Intermediates; vol. 42; 5; (2016); p. 4621 – 4640;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem

Name is Benzo[d]oxazole-2-thiol, as a common heterocyclic compound, it belongs to benzoxazole compound, and cas is 2382-96-9, its synthesis route is as follows.,2382-96-9

General procedure: The substituted 2-aminophenol (1eq.) in water and 95% ethanol was added potassium carbonate (1eq.) and CS2 (1eq.).The mixture was heated under reflux for 3 hours. After cooling, the solution was neutralized with 15 mL of acetic acid in 30 mL water. The precipitate was collected to give 2-thiolbenzoxazoles. Then, the substituted 2-thiolbenzoxazoles (1eq.) dissolved in toluene, PCl5 (1.5eq) was added dropwise. The mixture was heated to reflux for 2 hours. After the solvent was evaporated, the crude product was purified by silica gel column chromatography using PE-EA as an eluent.

With the complex challenges of chemical substances, we look forward to future research findings about Benzo[d]oxazole-2-thiol

Reference£º
Article; Ouyang, Liang; Huang, Yuhui; Zhao, Yuwei; He, Gu; Xie, Yongmei; Liu, Jie; He, Jun; Liu, Bo; Wei, Yuquan; Bioorganic and Medicinal Chemistry Letters; vol. 22; 9; (2012); p. 3044 – 3049;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem

2382-96-9, Benzo[d]oxazole-2-thiol is a benzoxazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

To a suspension of 1 (10 mmol, 1.51 g) in SOCl2 (50 mL) was added few drops of DMF, and the mixture heated at reflux for 5 h. After the solvent was evaporated, the crude product was purified by silica gel column chromatography (petroleum ether/EtOAc, 10:1). Colorless oil, yield 69.7%., 2382-96-9

As the paragraph descriping shows that 2382-96-9 is playing an increasingly important role.

Reference£º
Article; Wang, Guangcheng; Peng, Zhiyun; Wang, Jing; Li, Juan; Li, Xin; Bioorganic and Medicinal Chemistry; vol. 24; 21; (2016); p. 5374 – 5379;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem

2382-96-9, Benzo[d]oxazole-2-thiol is a benzoxazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: Boehmite-SSA (0.002 g) was added to a mixture of thiol(1 mmol) and H2O2 (0.4 mL) in ethyl acetate (2 mL). Then,the mixture was stirred for the appropriate time at room temperature. The progress of reaction was monitored byTLC. After completion of the reaction, the catalyst was separated by filtration and the mixture was washed with ethyl acetate. The product was extracted with ethyl acetate.The organic layer was dried over anhydrous Na2SO4(1.5 g). The products were obtained in good to high yield., 2382-96-9

As the paragraph descriping shows that 2382-96-9 is playing an increasingly important role.

Reference£º
Article; Ghorbani-Choghamarani, Arash; Hajjami, Maryam; Tahmasbi, Bahman; Noori, Nourolah; Journal of the Iranian Chemical Society; vol. 13; 12; (2016); p. 2193 – 2202;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem

Name is Benzo[d]oxazole-2-thiol, as a common heterocyclic compound, it belongs to benzoxazole compound, and cas is 2382-96-9, its synthesis route is as follows.,2382-96-9

General procedure: A mixture of thiol (1 mmol), 33 % H2O2 (0.4 mL) and Fe3O4MCM-41VO-SPATB (10 mg) in ethanol (3 mL) was stirred for the specified time at ambient temperature (the progress of reaction was monitored by TLC). After completion of the reaction, the catalyst was separated by applying an external magnet and the product was washed with ethyl acetate, and then dried over anhydrous Na2SO4 (1.5 g). Finally, Evaporation of the solvent gave the disulfides invery high isolated yields

With the complex challenges of chemical substances, we look forward to future research findings about Benzo[d]oxazole-2-thiol

Reference£º
Article; Nikoorazm, Mohsen; Ghorbani, Farshid; Ghorbani-Choghamarani, Arash; Erfani, Zahra; Journal of the Iranian Chemical Society; vol. 16; 3; (2019); p. 553 – 562;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem

Name is Benzo[d]oxazole-2-thiol, as a common heterocyclic compound, it belongs to benzoxazole compound, and cas is 2382-96-9, its synthesis route is as follows.,2382-96-9

EXAMPLE 16 Preparation of 2-[5-(N-(1H-benzoxazol-2-yl)-N-heptylamino)pentyl]thio-4,5-diphenyl-1H-imidazole Method A, Part A. A solution of 2-mercapto-1H-benzoxazole (5.85 g, 38.7 mmol), methyl iodide (2.70 mL, 43.4 mmol), and potassium carbonate (7.39 g, 53.5 mmol) in tetrahydrofuran (100 mL) was heated to reflux for 18 hours. After stirring at room temperature for an additional 24 hours, the solution was poured into (2*150 mL). The extracts were combined, dried over anhydrous magnesium sulfate, filtered and evaporated to afford sufficiently pure 2-methylthio-1-H-benzoxazole (6.27 g, 37.9 mmol, 98%) as a pale yellow oil.

With the complex challenges of chemical substances, we look forward to future research findings about Benzo[d]oxazole-2-thiol

Reference£º
Patent; The Du Pont Merck Pharmaceutical Company; US5364875; (1994); A;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem