Category: 2382-96-9

Benzo[d]oxazole-2-thiol, cas is 2382-96-9, it is a common heterocyclic compound, the benzoxazole compound, its synthesis route is as follows.,2382-96-9

General procedure: To a solution of 1 mmol of thiol in acetonitrile (2mL), was added a solution of 8 mL of phosphate buffer including laccase (40 U) and 4-phenyl urazole (10 mol%). The resulting mixture was stirred under air at room temperature for the time specified. After completion of the reaction (monitored by TLC), NaOH (10%, 10 mL). The combined organic phases were dried over anhydrous Na2SO4, filtered and evaporated under reduced pressure. The crude products were purified by recrystallization or chromatography on silica gel (n-hexane/EtOAc, 5/1). All the products were known and characterized by comparison of their spectral data (1H NMR) and physical properties (melting point) with those of authentic samples.

With the rapid development of chemical substances, we look forward to future research findings about 2382-96-9

Reference£º
Article; Khaledian, Donya; Rostami, Amin; Zarei, Seyed Amir; Catalysis Communications; vol. 114; (2018); p. 75 – 78;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem

2382-96-9, Benzo[d]oxazole-2-thiol is a benzoxazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Example 2 (Compound No. 8 in Table) Production of 9-(benzoxazol-2-ylthio)-N-(2-methylthio-3-pyridyl)nonanamide: The reaction and the treatment were conducted in the same manner as in Example 1 except that 9-bromononanoyl chloride was used instead of 6-bromohexanoyl chloride to obtain 9-bromo-N-(2-methylthio-3-pyridyl)nonanamide. To a DMF (5 ml) solution of this amide (90 mg, 0.25 mmol) and 2-mercaptobenzoxazole (38 mg, 0.25 mmol) were added potassium carbonate (42 mg, 0.30 mmol) and 18-crown-6 (7 mg, 0.03 mmol), and the mixture was stirred at 80C for 3 hours. The reaction mixture was allowed to cool, and then extracted with ethyl acetate. The organic layer was washed with water and then with a saturated aqueous solution of sodium chloride, and dried over sodium sulfate. Subsequently, the solvent was distilled off, and the resulting residue was recrystallized from a mixture of ethyl acetate-hexane to obtain 83 mg (yield 77%) of the desired compound as a colorless powdery crystal. Melting point: 84 – 85C IR (KBr) cm-1:3465, 3276, 2926, 1664, 1505., 2382-96-9

As the paragraph descriping shows that 2382-96-9 is playing an increasingly important role.

Reference£º
Patent; KOWA COMPANY LTD.; EP979823; (2000); A1;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.2382-96-9,Benzo[d]oxazole-2-thiol,as a common compound, the synthetic route is as follows.

General procedure: A mixture of thiol (1 mmol), 33 % H2O2 (0.4 mL) and Fe3O4MCM-41VO-SPATB (10 mg) in ethanol (3 mL) was stirred for the specified time at ambient temperature (the progress of reaction was monitored by TLC). After completion of the reaction, the catalyst was separated by applying an external magnet and the product was washed with ethyl acetate, and then dried over anhydrous Na2SO4 (1.5 g). Finally, Evaporation of the solvent gave the disulfides invery high isolated yields, 2382-96-9

2382-96-9 Benzo[d]oxazole-2-thiol 712377, abenzoxazole compound, is more and more widely used in various fields.

Reference£º
Article; Nikoorazm, Mohsen; Ghorbani, Farshid; Ghorbani-Choghamarani, Arash; Erfani, Zahra; Journal of the Iranian Chemical Society; vol. 16; 3; (2019); p. 553 – 562;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.2382-96-9,Benzo[d]oxazole-2-thiol,as a common compound, the synthetic route is as follows.

General procedure: In a typical procedure, a solution of thiol (1 mmol) and Fe3O4/AMPD/Ni (0.005 g) was added to a round-bottomed flask containing H2O2 (0.5 mL) and 2 mL of ethanol and stirred at room temperature for an appropriate time. After completion of the addition, Fe3O4/AMPD/Ni catalyst was easily separated by a simple magnet, and then the product was extracted with ethyl acetate and dried over anhydrous Na2SO4 to give the pure disulfides., 2382-96-9

The synthetic route of 2382-96-9 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Tamoradi, Taiebeh; Mehraban-Esfandiari, Bita; Ghadermazi, Mohammad; Ghorbani-Choghamarani, Arash; Research on Chemical Intermediates; vol. 44; 2; (2018); p. 1363 – 1380;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem

2382-96-9, Benzo[d]oxazole-2-thiol is a benzoxazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

To an oven dried flask equipped with a stir bar cooled under argon was added benzo[d]oxazole- 2(3H)-thione (0.375 grams, 2.48 mmol) and K2C03 (1.37, 9.92 mmol). The was taken up in 20.0 mL anhydrous acetone. After stirring for approximately minutes at room temperature, methyl iodide (0.25 mL, 3.97 mmol) was added. The solution continued to stir at room temperature overnight. The next day the solution was filtered through a plug of celite, and rinsed with dichloromethane and ethyl acetate. The solution was then concentrated. It was then taken up in ethyl acetate, filtered, and concentrated again. It was then used without further purification. Calculated mass for Chemical Formula: C8H7NOS Exact Mass: 165.02 observed 166.1 (M+l, MM API/ESI)., 2382-96-9

As the paragraph descriping shows that 2382-96-9 is playing an increasingly important role.

Reference£º
Patent; MUSC FOUNDATION FOR RESEARCH DEVELOPMENT; U.S. DEPARTMENT OF VETERANS AFFAIRS; LINDSEY, Christopher, C.; BEESON, Craig, C.; SCHNELLMANN, Rick, G.; (51 pag.)WO2018/85491; (2018); A1;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem

Benzo[d]oxazole-2-thiol, cas is 2382-96-9, it is a common heterocyclic compound, the benzoxazole compound, its synthesis route is as follows.,2382-96-9

General procedure: A mixture of thiols (1 mmol), UHP (5 mmol), and Co orFeMCM-41 (20 mg) was stirred at room temperature inethanol and the progress of the reaction was monitored by TLC.After completion of the reaction, the catalyst was removed andthe products were extracted with CH2Cl2 (3 ¡Á 10 mL). Theresults are shown in Table 7.

With the rapid development of chemical substances, we look forward to future research findings about 2382-96-9

Reference£º
Article; Noori, Nourolah; Nikoorazm, Mohsen; Ghorbani-Choghamarani, Arash; Phosphorus, Sulfur and Silicon and the Related Elements; vol. 191; 10; (2016); p. 1388 – 1395;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.2382-96-9,Benzo[d]oxazole-2-thiol,as a common compound, the synthetic route is as follows.

Specifically include:Solid phosgene (BTC) is selected as the chlorinating agent.2 mmol of 2-mercaptobenzoxazole prepared in the step 1 was added to the flask.Add 10 mL of toluene or cyclohexane as solvent to the flask.4 mmol of solid triphosgene was added to the flask.Warm up to 50 C under magnetic stirring, keep warm for 10 min, and then slowly heat up.Each temperature is raised at 10 C for 10 min, when the temperature is raised to 105 C, the temperature is kept for 1 h; TCL point plate analysis,Properly extend the reaction time,After separation by column chromatography, 0.142 g of 2-chlorobenzoxazole was obtained.The product was slightly yellowish liquid with a yield of 46%., 2382-96-9

The synthetic route of 2382-96-9 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Chen Wantong; (5 pag.)CN108794421; (2018); A;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem

Benzo[d]oxazole-2-thiol, cas is 2382-96-9, it is a common heterocyclic compound, the benzoxazole compound, its synthesis route is as follows.,2382-96-9

General procedure: For the fabrication of sulfoxide, 1 mmol sulfide, 0.6 ml H2O2 (33%) and 0.005 g nanocatalyst were stirred at room temperature. Also, for producing disulfides, 1 mmol thiols and 0.4 ml H2O2 (33%) with 0.008 g nanocatalyst in ethanol as a green solvent were mixed at 25 C. After completion of the reaction, the catalyst was removed by a magnet and the product was extracted with ethyl acetate and dried using a vacuum dryer.

With the rapid development of chemical substances, we look forward to future research findings about 2382-96-9

Reference£º
Article; Moeini, Nazanin; Ghadermazi, Mohammad; Ghorbani-Choghamarani, Arash; Polyhedron; vol. 170; (2019); p. 278 – 286;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem