Category: 27231-36-3

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 2-Mercapto-5-methylbenzimidazole, is researched, Molecular C8H8N2S, CAS is 27231-36-3, about In vitro metabolism of 4-methyl- and 5-methyl-2-mercaptobenzimidazole, thyrotoxic and hepatotoxic rubber antioxidants, in rat liver microsomes.Application In Synthesis of 2-Mercapto-5-methylbenzimidazole.

The metabolism of 4-methyl-2-mercaptobenzimidazole (4-MeMBI), 5-methyl-2-mercaptobenzimidazole (5-MeMBI), and 2-mercaptobenzimidazole (MBI) was examined in vitro in rat liver microsomes. The test chems. were incubated in the presence of liver microsomes from male Sprague-Dawley rats, and their metabolism was analyzed by HPLC. The metabolism amount increased in an incubation time-dependent manner, and was similar among the test chems. SKF-525A, a non-selective inhibitor of cytochrome P 450 (CYP) enzymes, decreased the metabolic rate of all the test chems., indicating the involvement of liver microsomal CYP enzymes. When liver microsomes from rats treated with CYP-inducers (β-naphthoflavone, phenobarbital, and isoniazid) were used, 4-MeMBI was more decreased than 5-MeMBI, particularly in the phenobarbital-treated group. These results, together with the reported inducibility of the drug-metabolizing activity by the test chems., partly explained the counteraction in the toxic effects between 4-MeMBI and 5-MeMBI in the in vivo study.

This compound(2-Mercapto-5-methylbenzimidazole)Application In Synthesis of 2-Mercapto-5-methylbenzimidazole was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 2-Mercapto-5-methylbenzimidazole, is researched, Molecular C8H8N2S, CAS is 27231-36-3, about 2-(3-Bromo-1-phenylsulfonyl-RH-indol-2-ylmethylsulfanyl)-6-methyl-1H-benzimidazole.Computed Properties of C8H8N2S.

In the title compound, C23H18BrN3O2S2, the sulfonyl-bound Ph ring and benzimidazole moiety are nearly orthogonal to the indole ring system. The mol. structure is stabilized by C-H···Br and C-H···O H bonding interactions. In the crystal structure, glide-related mols. are linked by N-H···N H bonds to form chains along the c axis and adjacent chains are interlinked by C-H···π interactions into a three-dimensional network. Crystallog. data are given.

This compound(2-Mercapto-5-methylbenzimidazole)Computed Properties of C8H8N2S was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Liu, Xing; Liu, Min; Xu, Wan; Zeng, Meng-Tian; Zhu, Hui; Chang, Cai-Zhu; Dong, Zhi-Bing published an article about the compound: 2-Mercapto-5-methylbenzimidazole( cas:27231-36-3,SMILESS:SC1=NC2=CC(C)=CC=C2N1 ).Formula: C8H8N2S. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:27231-36-3) through the article.

An efficient and practical method for the one-step synthesis of benzothiazole-2-thiols I [R = H, 5-Cl; X = S], benzoxazole-2-thiols I [R = H, 5-Me, 5-Br, etc.; X = O] and benzimidazoline-2-thiones such as II by cyclization of 2-aminothiophenols, 2-aminophenols, and 1,2-phenylenediamines with tetramethylthiuram disulfide (TMTD) in water was described. This method was also used for the synthesis of 4,5-dihydro-thiazole-2-thiol, 4,5-dihydro-oxazole-2-thiol and 1,3-ethylenethiourea from their corresponding aliphatic amines and (TMTD). The features of this method included metal/ligand-free, excellent yield, short reaction time and broad substrate scope. The method provided a facile and convenient preparation of some potentially biol. active compounds

This compound(2-Mercapto-5-methylbenzimidazole)Formula: C8H8N2S was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Qiu, Qi-Ming; Liu, Min; Li, Zhong-Feng; Jin, Qiong-Hua; Huang, Xu; Zhang, Zhen-Wei; Zhang, Cun-Lin; Meng, Qing-Xuan researched the compound: 2-Mercapto-5-methylbenzimidazole( cas:27231-36-3 ).SDS of cas: 27231-36-3.They published the article 《Synthesis, structure, terahertz spectroscopy and luminescent properties of copper(I) complexes with mercaptan ligands and triphenylphosphine》 about this compound( cas:27231-36-3 ) in Journal of Molecular Structure. Keywords: preparation copper mercaptothiazole phosphine complex; crystal structure copper mercaptothiazole phosphine complex; fluorescence copper mercaptothiazole phosphine complex. We’ll tell you more about this compound (cas:27231-36-3).

The reactions of Cu(I) halides with PPh3 (PPh3) and mercaptan ligand [2-mercapto-6-nitrobenzothiazole (HMNBT), 2-amino-5-mercapto-1,3,4-thiadiazole (HAMTD) and 2-mercapto-5-methyl-benzimidazole (MMBD)] yielded seven complexes, [CuCl(HMNBT)(PPh3)2] (1), [CuX(HMNBT)(PPh3)]2 (X = Cl, Br) (2-3), [Cu(MNBT)(HMNBT)(PPh3)2] (4), [CuBr(HAMTD)(PPh3)2]·MeOH (5) and [CuX(MMBD)(PPh3)2]·2MeOH (X = Br, I) (6-7). These complexes were characterized by elemental anal., x-ray diffraction, 1H NMR and 31P NMR spectroscopy. In these complexes the mercaptan ligands act as monodentate or bridged ligand with S as the coordination atom. In complexes 1 and 4, H bonds CH···X and weak interactions CH···π give chains and 2-dimensional network, resp., while complexes 2 and 3 are dinuclear. In 5-7, intramol. H bonds link the [CuX(thione)(PPh3)2] mols. and the solvated MeOH mols. into centrosym. dimers. Complexes 1-5 represent 1st Cu(I) halide complexes of HMNBT and HAMTD. The complexes 1, 5, 6 and 7 exhibit interesting fluorescence in the solid state at room temperature and their terahertz (THz) time-domain spectroscopy was also studied.

This compound(2-Mercapto-5-methylbenzimidazole)SDS of cas: 27231-36-3 was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Reference of 2-Mercapto-5-methylbenzimidazole. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 2-Mercapto-5-methylbenzimidazole, is researched, Molecular C8H8N2S, CAS is 27231-36-3, about Thermodynamic and electrochemical properties of imidazole-2-thiols (imidazole-2(3H)-thiones). Author is Po, Henry N.; Shariff, Zarila; Masse, Jeffrey A.; Freeman, Fillmore; Keindl-Yu, Monica C..

The oxidation and reduction potentials for eight imidazole-2-thiols [imidazole-2-thio (1a), 1-methyl- (1b), 4,5-dimethyl- (1c), 1,4,5-trimethyl- (1d), 4,5-diphenyl- (1e), benz- (1f), 5-methylbenz- (1g), and 5-nitrobenzimidazole-2-thiol (1h)] have been determined in ethanenitrile-hydrogen chloride solution Substituent effects on E(ox) are observed and are discussed. The pKa’s for thiols 1a, 1b, and 1c have been determined as a function of pH in buffer solutions at five temperatures and constant ionic strength of 0.10M using UV spectroscopy. The ΔH0 (kJ/mol) and ΔS° (J mol-1 K-1) for imidazole-2-thiol (1a), 1-methylimidazole-2-thiol (1b), and 4,5-dimethylimidazole-2-thiol (1c) are 38.2 and -92.9, 34.1 and -107.5, and 45.2 and -80.3, resp.

This compound(2-Mercapto-5-methylbenzimidazole)Reference of 2-Mercapto-5-methylbenzimidazole was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Whitcomb, D. R.; Swatloski, Richard P.; Rogers, Robin D. published an article about the compound: 2-Mercapto-5-methylbenzimidazole( cas:27231-36-3,SMILESS:SC1=NC2=CC(C)=CC=C2N1 ).Recommanded Product: 2-Mercapto-5-methylbenzimidazole. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:27231-36-3) through the article.

The reaction of 5-methyl-2-mercaptobenzimidazole (5MBI) with silver ions in organic solvents form widely varying macrostructured or polymeric structures, depending on the anion type. In the case of carboxylate anions, the reaction of 5MBI with [Ag(O2CxH2x-1)]2 results in high yields of hexameric clusters containing bridging 5MBI units, [Ag·5MBI·THF]6, the details of which are reported here. The six silver atoms of [Ag·5MBI]6 are arranged as a trigonal antiprism with each 5MBI bonded to three silver atoms, two bridged with the sulfur and the 3rd bridged with the nitrogen. And comparison to the reaction of AgBr that forms a polymeric [AgBr·MBI(acetone)0.5]4 complex, a mixture of different complexes may be expected to form in a photothermog. imaging construction.

This compound(2-Mercapto-5-methylbenzimidazole)Recommanded Product: 2-Mercapto-5-methylbenzimidazole was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Quality Control of 2-Mercapto-5-methylbenzimidazole. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: 2-Mercapto-5-methylbenzimidazole, is researched, Molecular C8H8N2S, CAS is 27231-36-3, about The effects of simultaneous treatment of SiO2 gate and Au electrode with octadecyltrichlorosilane and charge transfer molecules on characteristics of pentacene thin film transistors. Author is Pyo, Kyung Soo; Song, Chung Kun.

The authors studied the effects of treatment with octadecyltrichlorosilane (OTS) and the charge transfer mols. (CTM) such as 2-mercapto-5-nitrobenzimidazole (MNB), 2-mercapto-benzoxazole (MBX), 2-mercapto-benzthiazole (MBT), and 2-mercapto-5-methylbenzimidazole (MMB) on SiO2 and Au electrode on pentacene organic thin film transistors (OTFTs). Especially for improvement of the mobility and the contact resistance at the same time, the authors simultaneously treated SiO2 and Au electrode with OTS, MNB, and MBX. As the results, the authors could improve the mobility to 0.2 cm2/V s and reduce the contact resistance to 50 kΩ, corresponding to 10 times larger than the untreated OTFTs.

《The effects of simultaneous treatment of SiO2 gate and Au electrode with octadecyltrichlorosilane and charge transfer molecules on characteristics of pentacene thin film transistors》 provides a strategy for the preparation of materials with excellent comprehensive properties, which is conducive to broaden the application field of this compound(2-Mercapto-5-methylbenzimidazole)Quality Control of 2-Mercapto-5-methylbenzimidazole.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Sarada, R.; Jagannadharao, V.; Padma, M.; Sundar, B. Syama published the article 《Catalytic application of synthesized capped silver nanoparticles for reduction of p-nitroaniline》. Keywords: nitroaniline reduction capped silver nanoparticle catalyst.They researched the compound: 2-Mercapto-5-methylbenzimidazole( cas:27231-36-3 ).Recommanded Product: 2-Mercapto-5-methylbenzimidazole. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:27231-36-3) here.

Catalytic activity of synthesized capped silver nanoparticles was performed in the reduction of p-phenylene diamine from p-nitroaniline in the presence of reducing agent sodium borohydride. The rate of reduction is observed with nanoparticles having different sizes 40, 20 and 40 ± 2 nm. The product obtained in the presence of 20 nm size nanoparticles is in good yield and produced in less time when compared to other nanoparticles. Moreover it is observed that this catalyst showed maximum efficiency at 1 mM concentration and also act as potential recyclable catalyst.

《Catalytic application of synthesized capped silver nanoparticles for reduction of p-nitroaniline》 provides a strategy for the preparation of materials with excellent comprehensive properties, which is conducive to broaden the application field of this compound(2-Mercapto-5-methylbenzimidazole)Recommanded Product: 2-Mercapto-5-methylbenzimidazole.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Copper-catalyzed aminothiolation of terminal alkynes with tunable regioselectivity, published in 2019, which mentions a compound: 27231-36-3, mainly applied to thiazolobenzimidazole preparation regioselective; terminal alkyne regioselective cycloaddition mercaptobenzimidazole aminothiolation copper catalyst, Formula: C8H8N2S.

A simple, mild, and efficient copper(I)-catalyzed aminothiolation of terminal alkynes R1CCH (R1 = HOCH2CH2, Me3Si, cyclohexen-1-yl, Ph, pyridin-2-yl, etc.) with 5-R2-substituted 2-mercaptobenzimidazoles (R2 = H, Me, MeO, O2N) gave both 2- and 3-substituted thiazolo[3,2-a]benzimidazoles I, where complementary regioselectivities could be achieved by using sterically different phenanthroline-based ligands, such as 1,10-phenanthroline and 2,9-diisopropyl-1,10-phenanthroline.

《Copper-catalyzed aminothiolation of terminal alkynes with tunable regioselectivity》 provides a strategy for the preparation of materials with excellent comprehensive properties, which is conducive to broaden the application field of this compound(2-Mercapto-5-methylbenzimidazole)Formula: C8H8N2S.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Recommanded Product: 2-Mercapto-5-methylbenzimidazole. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: 2-Mercapto-5-methylbenzimidazole, is researched, Molecular C8H8N2S, CAS is 27231-36-3, about Trans-1,2-bis(diphenylphosphino)ethene as bridging ligand in thione-S-ligated dimeric copper(I) chloride complexes. Author is Aslanidis, P.; Cox, P. J.; Divanidis, S.; Karagiannidis, P..

Several mixed-ligand complexes were prepared by treatment of Cu(I) chloride with equimolar amounts of trans-1,2-bis(diphenylphosphino)ethene (trans-dppen) in MeCN followed by the addition of a methanolic solution of one equivalent of a heterocyclic thione (L). The novel complex compounds were characterized by single-crystal x-ray diffraction, 1H NMR and IR spectroscopy as well as by elemental analyses and m.ps. The x-ray structures of three examples confirm that the compounds are homobimetallic dimers [CuCl(μ2-trans-dppen)(L)]2 containing two tetrahedral coordination units joined by two trans-dppen bridges.

《Trans-1,2-bis(diphenylphosphino)ethene as bridging ligand in thione-S-ligated dimeric copper(I) chloride complexes》 provides a strategy for the preparation of materials with excellent comprehensive properties, which is conducive to broaden the application field of this compound(2-Mercapto-5-methylbenzimidazole)Recommanded Product: 2-Mercapto-5-methylbenzimidazole.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem