Category: 27231-36-3

Lazer, Edward S.; Matteo, Martha R.; Possanza, Genus J. published the article 《Benzimidazole derivatives with atypical antiinflammatory activity》. Keywords: benzimidazole trifluoroethylsulfonyl preparation antiinflammatory; antiinflammatory trifluoroethylsulfonylbenzimidazole.They researched the compound: 2-Mercapto-5-methylbenzimidazole( cas:27231-36-3 ).Name: 2-Mercapto-5-methylbenzimidazole. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:27231-36-3) here.

The 2-[(2,2,2-trifluorooethyl)sulfonyl]-1H-benzimidazoles I (R = H, 5-Me, 5-Cl, 5-F, 5-Et, 5-Me-6-F, 5,6-Me2, 5-MeO2C, 5-CF3, 5-Pr) were prepared by alkylation of the corresponding 2-mercaptobenzimidazole followed by oxidation

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Reference:
Benzoxazole – Wikipedia,
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The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 2-Mercapto-5-methylbenzimidazole( cas:27231-36-3 ) is researched.HPLC of Formula: 27231-36-3.Abreu-Quijano, M.; Palomar-Pardave, M.; Cuan, A.; Romero-Romo, M.; Negron-Silva, G.; Alvarez-Bustamante, R.; Ramirez-Lopez, A.; Herrera-Hernandez, H. published the article 《Quantum chemical study of 2-mercaptoimidazole, 2-mercaptobenzimidazole, 2-mercapto-5-methylbenzimidazole and 2-mercapto-5-nitrobenzimidazole as corrosion inhibitors for steel》 about this compound( cas:27231-36-3 ) in International Journal of Electrochemical Science. Keywords: m mercaptoimidazole corrosion inhibitor steel density functional theory. Let’s learn more about this compound (cas:27231-36-3).

In order to analyze the influence of substituent groups, both electron-donating and electron-attracting and the number of π-electrons on the corrosion inhibiting properties of organic mols., a theor. quantum chem. study under vacuo and in the presence of water, using the Polarizable Continuum Model (PCM), was carried out for four different mols., bearing similar chem. framework structure: 2-mercaptoimidazole (2MI), 2-mercaptobenzimidazole (2MBI), 2-mercapto-5-methylbenzimidazole (2M5MBI), and 2-mercapto-5-nitrobenzimidazole (2M5NBI). From an electrochem. study conducted previously in our group, it was found that the corrosion inhibition efficiency, IE, order followed by the mols. tested was 2MI > 2MBI > 2M5MBI > 2M5NBI. Thus 2MI turned out to be the best inhibitor. This fact strongly suggests that, contrary to a hitherto generally suggested notion, an efficient corrosion inhibiting mol. neither requires to be a large one, nor possesses an extensive π-electrons number In this work, from a theor. study a correlation was found between EHOMO, hardness (η), electron charge transfer (ΔN), electrophilicity (W), back-donation (ΔEBack-donation) and the inhibition efficiency, IE. The neg. values of EHOMO and the estimated value of the Standard Free Gibbs energy for all the mols. (based on the calculated equilibrium constant) were neg., indicating that the complete chem. processes in which the inhibitors are involved, occur spontaneously.

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In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Studies on proton pump inhibitors. I. Synthesis of 8-[(2-benzimidazolyl)sulfinyl]-5,6,7,8-tetrahydroquinolines and related compounds, published in 1989-06-30, which mentions a compound: 27231-36-3, mainly applied to benzimidazolylsulfinyltetrahydroquinoline preparation antisecretory antiulcer; structure activity benzimidazolylsulfinyltetrahydroquinoline, Related Products of 27231-36-3.

Many 8-[(2-benzimidazolyl)sulfinyl]-5,6,7,8-tetrahydroquinolines were synthesized and examined for their (H+ + K+) ATPase ATPase-inhibitory and antisecretory activities. These sulfinyl compounds could be considered to be rigid analogs of the 2-[(2-pyridyl)methylsulfinyl]benzimidazole class of antisecretory agents. All the compounds tested were potent inhibitors of (H+ + K+)ATPase. Most of the compounds also inhibited histamine-induced gastric acid secretion in rats. Among them, 8-[(5-fluoro-2-benzimidazolyl)sulfinyl]-3-methyl-5,6,7,8-tetrahydroquinoline (I) was found to have the most potent activity. The structure-activity relationships are discussed.

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Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 27231-36-3, is researched, SMILESS is SC1=NC2=CC(C)=CC=C2N1, Molecular C8H8N2SJournal, Japanese Journal of Toxicology and Environmental Health called Analysis of 2-mercaptobenzimidazole type antioxidants in rubber products, Author is Isama, Kazuo; Kaniwa, Masa-aki; Nakamura, Akitada, the main research direction is mercaptobenzimidazole antioxidant analysis HPLC rubber boot.Recommanded Product: 2-Mercapto-5-methylbenzimidazole.

A method for the determination of 2-mercaptobenzimidazole (MBI) type antioxidants in rubber products by HPLC was developed. The anal. conditions to sep. 2-mercapto-4-methylbenzimidazole (4MMBI) from 2-mercapto-5-methylbenzimidazole (5MMBI) by HPLC and to extract MBI type antioxidants from rubber products were examined in detail. The recommended method was as follows. MBI type antioxidants was extracted with MeOH 5 times. The evaporation residue of the extract was dissolved in water and injected to HPLC. The HPLC conditions were as follows: column, CAPCELL PAK C18 (4.6 i.d. × 250 mm); column temperature, 40°; mobile phase, 0.1 M phosphate buffer (pH 6.5)-acetonitrile (87:13); flow rate, 1.0 mL/min; detection wavelength 304 nm (MBI, 4MMBI) and 307 nm (5MMBI). This method was applied to determine MBI type antioxidants in 12 com. rubber boots. Consequently, 11.5-67.7 μg/g of MBI was detected in 4 samples, but 4MMBI and 5MMBI were not detected in any samples.

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Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Antihelminthic activity of some newly synthesized 5(6)-(un)substituted-1H-benzimidazol-2-ylthioacetylpiperazine derivatives, published in 2006-12-31, which mentions a compound: 27231-36-3, mainly applied to benzimidazolyl thioacetyl piperazine derivative preparation antihelminthic agent; benzimidazole thio piperazinyl derivative preparation antihelminthic agent preparation, Product Details of 27231-36-3.

Piperazine derivatives of 5(6)-substituted-(1H-benzimidazol-2-ylthio)acetic acids were synthesized by using two methods and studied for antihelminthic activity. The antiparasitic screening showed that the synthesized compounds exhibited higher activity against Trichinella spiralis in vitro in comparison to Me 5-(propylthio)-1H-benzimidazol-2-yl-carbamate (albendazole), the most active being, e.g., I (R = H or Me). All the compounds were less active against Syphacia obvelata in vivo than albendazole and exhibited the same efficacy as piperazine, but in twice lower concentration

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HPLC of Formula: 27231-36-3. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 2-Mercapto-5-methylbenzimidazole, is researched, Molecular C8H8N2S, CAS is 27231-36-3, about Mechanism of formation of 3-methyl derivatives of imidazo[2,1-b]thiazoles and their benzo analogs in the reactions of 2-mercaptoimidazole and 2-mercaptobenzimidazole with 1,3-dichloroacetone under phase-transfer catalysis conditions. Author is Beresneva, T.; Belyakov, S.; Abele, E.; Lukevics, E..

The mechanism of the unexpected formation of 3-Me derivatives of imidazo[2,1-b]thiazoles in the system 2-mercaptoimidazole/1,3-dichloroacetone/solid K2CO3/solid KI/18-crown-6/toluene was studied. The mol. structure of 3-methyl[1,3]thiazolo[3,2-a]benzimidazole was confirmed using x-ray structural anal. [monoclinic, space group P21/n, a 7.0531(2), b 12.9645(4), c 9.9273(4) Å, β 100.753(1)°, V 891.81(5) Å3, Z 4].

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Benzoxazole – Wikipedia,
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Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 27231-36-3, is researched, Molecular C8H8N2S, about Improved contact properties for organic thin-film transistors using self-assembled monolayer, the main research direction is self assembled monolayer organic thin film transistor carrier injection.Category: benzoxazole.

Contact properties between the organic semiconductor and the metal source and drain contacts are one of the most important issues since the charge carrier injection through the contact has serious effects on the device performance. Gold (Au) surfaces of the source and drain electrodes are modified using self-assembled monolayers (SAMs) using thiol derivatives The charge carrier mobility was increased from 0.1 to 0.48 cm2/V·s after the modification of the source and drain electrodes. Mobilities and saturation currents seem to be governed more effectively by the contact properties than by the work function difference between the (modified) electrodes and organic semiconductor.

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Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Research Support, Non-U.S. Gov’t, Journal of Organic Chemistry called Copper- and Palladium-Catalyzed Cross-Coupling Reactions for the Synthesis of N-Fused Benzo[4,5]imidazo[2,1-b]thiazole Derivatives via Substituted trans-1,2-Diiodoalkenes, 1H-Benzo[d]imidazole-2-thiols, and Halobenzenes, Author is Shen, Guodong; Yang, Bingchuan; Huang, Xianqiang; Hou, Yaxin; Gao, Huan; Cui, Jichun; Cui, Chuansheng; Zhang, Tongxin, which mentions a compound: 27231-36-3, SMILESS is SC1=NC2=CC(C)=CC=C2N1, Molecular C8H8N2S, Safety of 2-Mercapto-5-methylbenzimidazole.

In the presence of CuI, 1,10-phenanthroline, and K2CO3 in DMF, 2-benzimidazolethiols underwent cross-coupling and cyclization reactions with (E)-1,2-diiodoalkenes such as (E)-PhCI:CHI to yield benzimidazothiazoles such as I (R = H) in 66-83% yields. In the presence of Pd(OAc)2, Ph3P, and Cs2CO3 in p-xylene, benzimidazothiazoles such as I (R = H) underwent arylation with aryl iodides RI (R = Ph, 2-MeC6H4, 3-MeC6H4, 4-MeC6H4, 4-ClC6H4) and bromobenzene to yield arylbenzimidazothiazoles such as I (R = Ph, 2-MeC6H4, 3-MeC6H4, 4-MeC6H4, 4-ClC6H4) in 65-96% yields. The structure of I (R = Ph) was determined by X-ray crystallog.

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SDS of cas: 27231-36-3. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 2-Mercapto-5-methylbenzimidazole, is researched, Molecular C8H8N2S, CAS is 27231-36-3, about A new route for the synthesis of 2-mercapto benzimidazoles. Author is Ambati, Narahari Babu; Babu, V. N. S. Ramesh; Anand, V.; Hanumanthu, P..

Bis(methylthioureido) benzenes I [R = H, Me, MeO, Cl, O2N; R1 = NHC(:S)NHMe] were prepared in 72-89% yields by treatment of benzenediamines II [R = H, Me, MeO, Cl, O2N; R1 = NH2] with Me isothiocyanate. I are refluxed in 1,4-dioxane to give benzimidazolethiols II (R = H, Me, MeO) in 89-92% yields and N,N’-dimethylthiourea as a side product.

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Benzoxazole – Wikipedia,
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