Category: 3194-15-8

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 1-(Furan-2-yl)propan-1-one(SMILESS: O=C(C1=CC=CO1)CC,cas:3194-15-8) is researched.Reference of Tris(2,2′-bipyridine)ruthenium bis(hexafluorophosphate). The article 《Additive-Free Isomerization of Allylic Alcohols to Ketones with a Cobalt PNP Pincer Catalyst》 in relation to this compound, is published in Chemistry – A European Journal. Let’s take a look at the latest research on this compound (cas:3194-15-8).

Catalytic isomerization of allylic alcs. in ethanol as a green solvent was achieved by using air and moisture stable cobalt (II) complexes in the absence of any additives. Under mild conditions, the cobalt PNP pincer complex substituted with Ph groups on the phosphorus atoms appeared to be the most active. High rates were obtained at 120°, even though the addition of one equivalent of base increases the speed of the reaction drastically. Although some evidence was obtained supporting a dehydrogenation-hydrogenation mechanism, it was proved that this is not the major mechanism. Instead, the cobalt hydride complex formed by dehydrogenation of ethanol was capable of double-bond isomerization through alkene insertion-elimination.

This compound(1-(Furan-2-yl)propan-1-one)Electric Literature of C7H8O2 was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Recommanded Product: 3194-15-8. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: 1-(Furan-2-yl)propan-1-one, is researched, Molecular C7H8O2, CAS is 3194-15-8, about Synthesis of thienyl and furyl 1,2,3-selenadiazole. Author is Kurban, Osman; Minawar, Yemenaishan.

A method for the synthesis of thienyl and furyl 1,2,3-selenadiazoles I (R = H, Me, X = O, S) is reported. Four new compounds were prepared by this method. The compounds were characterized by IR, 1H NMR, and elemental anal.

This compound(1-(Furan-2-yl)propan-1-one)Recommanded Product: 3194-15-8 was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 3194-15-8, is researched, Molecular C7H8O2, about Photocatalytic C-C Bond Activation of Oxime Ester for Acyl Radical Generation and Application, the main research direction is oxindole cyclobutane preparation photocatalytic carbon bond activation oxime ester.Computed Properties of C7H8O2.

A unified strategy to generate acyl radical from oxime ester via selective C-C bond activation is reported. Under visible-light irradiation, single-electron transfer from fac-Ir(ppy)3 to related oxime takes place followed by a fast β-fragment of C-C bond to yield aryl and aliphatic acyl radicals, subsequently captured by diverse Michael acceptors. More interestingly, the single-electron transfer enables coupling with energy transfer of the excited fac-Ir(ppy)3 via enone intermediate formed in situ for cyclobutane formation.

《Photocatalytic C-C Bond Activation of Oxime Ester for Acyl Radical Generation and Application》 provides a strategy for the preparation of materials with excellent comprehensive properties, which is conducive to broaden the application field of this compound(1-(Furan-2-yl)propan-1-one)Computed Properties of C7H8O2.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Computed Properties of C7H8O2. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 1-(Furan-2-yl)propan-1-one, is researched, Molecular C7H8O2, CAS is 3194-15-8, about Volatile compounds produced in Maillard reactions involving cysteine, ribose and phospholipid. Author is Farmer, Linda J.; Mottram, Donald S.; Whitfield, Frank B..

The interaction of phospholipid in the Maillard reaction between cysteine and reducing sugars is of importance in the formation of meat flavor. The major volatile products of the aqueous reaction between cysteine and ribose, in the absence and presence of phospholipid, were studied by gas chromatog. (GC)-mass spectrometry and GC-IR spectroscopy, and the individual odors assessed by sensory evaluation of the GC effluent. Without phospholipid, S-containing heterocyclic Maillard products predominated, while the inclusion of phospholipid added lipid degradation products as well as certain compounds specific to the interaction of lipid in the Maillard reaction. The phospholipid also has a marked effect in the overall odor of the reaction mixtures and on the nature of the individual aromas detected.

《Volatile compounds produced in Maillard reactions involving cysteine, ribose and phospholipid》 provides a strategy for the preparation of materials with excellent comprehensive properties, which is conducive to broaden the application field of this compound(1-(Furan-2-yl)propan-1-one)Computed Properties of C7H8O2.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 3194-15-8, is researched, SMILESS is O=C(C1=CC=CO1)CC, Molecular C7H8O2Journal, Monatsschrift fuer Brauwissenschaft called The use of oats in brewing, Author is Hanke, S.; Zarnkow, M.; Kreisz, S.; Back, W., the main research direction is oat beer brewing malting history.Related Products of 3194-15-8.

Oats (Avena sativa) are one of the most popular cereals for human consumption. In the middle ages oats were the brewing cereal par excellence. Over the centuries they were substituted by other cereals and their brewing properties were nearly forgotten. Today oats are popular once more because of their excellent health-related properties. For people who suffer with celiac disease oats are also of interest. Based on their historical use in brewing and their health-related properties pilot malting trials were carried out with different varieties, followed by brewing trials with a selected variety. The results obtained showed that oat malt is an appropriate choice for brewing.

《The use of oats in brewing》 provides a strategy for the preparation of materials with excellent comprehensive properties, which is conducive to broaden the application field of this compound(1-(Furan-2-yl)propan-1-one)Related Products of 3194-15-8.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Synthetic Route of C7H8O2. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 1-(Furan-2-yl)propan-1-one, is researched, Molecular C7H8O2, CAS is 3194-15-8, about Unusual course of the Meerwein reaction in the furan series. Author is Markova, I. G.; Polievktov, M. K.; Oleinik, A. F.; Modnikova, G. A..

Meerwein reaction of p-XC6H4N2+ Cl- (X = Cl, Br, NO2) with furyl ketones I (R = Me, Et, Pr) gave II and III. II is not an intermediate in the formation of III. Polarog. indicated that RCHO were present in the reaction mixture which agreed with IV as a proposed intermediate; IV lost RCHO to give III.

The article 《Unusual course of the Meerwein reaction in the furan series》 also mentions many details about this compound(3194-15-8)Synthetic Route of C7H8O2, you can pay attention to it, because details determine success or failure

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 1-(Furan-2-yl)propan-1-one, is researched, Molecular C7H8O2, CAS is 3194-15-8, about Furylalkynes. IX. Transformations of furylethynylcarbinol and its derivatives.Synthetic Route of C7H8O2.

A solution of EtMgBr, prepared from 65.4 g. EtBr, in 560 ml. dry tetrahydrofuran (THF) was added dropwise to a solution of acetylene in THF (C2H2 was bubbled into THF 0.5 hr. at 0°). Fresh distilled furfural (54 g.) in the same volume THF was added after 30 min., the mixture was stirred 6 hrs. with simultaneous addition of C2H2, kept overnight, and decomposed with dilute NH4Cl to give 62% Ia, b2 83-5°, n20D 1.5040. Acrylonitrile (2.67 g.) was added to a stirred mixture of 5 g. Ia in 1 ml. 4% KOH at <30°. The mixture was stirred 6 hrs. at room temperature, kept overnight, and extracted with Et2O to yield 79.1% Ib, b0.5 142°, n20D 1.4968. HCl (1-2 drops) was added carefully to a stirred mixture of 5 g. Ia and 4.1 g. vinyl ethyl ether at 0°. The mixture was stirred 1 hr. at 0°, then 1 hr. at room temperature, added to 50 ml. cold H2O, and extracted with Et2O to yield 64% Ic, b2 72°, n20D 1.4695. Ic (5 g.) in 50 ml. EtOH was hydrogenated in the presence of 0.01 g. Raney Ni at room temperature/atm. pressure to give 96% II, b1.5 55-7°, n20D 1.4420. Ic (5 g.), 25 ml. dioxane, 1.26 g. HNMe2, and 1.75 g. paraformaldehyde were boiled 18 hrs. in a sealed tube to yield 4.5 g. Id, b1.5 105-7°, n20D 1.4720. Similarly was prepared 40% Ie, b1 142-3°, n20D 1.4931. An ether solution of 5 g. Ic was added dropwise to a solution of EtMgBr (from 5.6 g. EtBr), the mixture was stirred 7 hrs. at room temperature, kept overnight, 2.7 g. cyclohexanone in the same volume of Et2O was added to the vigorously stirred reaction mixture at 0° which was then stirred 20 hrs. and decomposed with dilute NH4Cl to yield 32% If, b6 125-7°, n20D 1.4900. Active MnO2 (35 g.) was added gradually to a cold solution of 5 g. Ia in 150 ml. Et2O and the mixture stirred 1 hr. at room temperature to give 91% 3-(2-furyl)-1-propyn-3-one (III), m. 43-6°. III (2 g.) was hydrogenated in alc. solution at room temperature to yield 3-(2-furyl)propan-3-one; 2,4-dinitrophenylhydrazone m. 194-6° (aqueous EtOH). III (1 g.) was added to an ether solution of CH2N2 prepared from 5 g. nitrosomethylurea and the mixture was kept overnight to give 76.4% IV, m. 199-200° (benzene-petroleum ether); 2,4-dinitrophenylhydrazone m. 225-6° (EtOH). A mixture of 2 g. III, 1.6 g. Et2NH, and 50 ml. Me2CO was stirred 6 hrs. at room temperature, and kept overnight to yield 76.4% V, b1 142-4°. Similarly were prepared 85.2% VI, b3 150-5°, m. 79-80°, and VII, m. 88-90°. Cu2Cl2 (0.5 g.) and 6 ml. 30% aqueous EtNH2 was added to a cool solution of 3.7 g. Ia in MeOH, 5.5 g. PhC:CBr and 0.1 g. NH2OH.HCl was added, and the mixture was stirred 30 min. at the room temperature KCN (0.1 g.) in 3 ml. H2O was added, the mixture was added to water, extracted with Et2O; the organic layer was stirred 4 hrs. with 60 g. active MnO2 to give 6.5 g. VIII m. 85.5-6.5°. 6 references. The article 《Furylalkynes. IX. Transformations of furylethynylcarbinol and its derivatives》 also mentions many details about this compound(3194-15-8)Synthetic Route of C7H8O2, you can pay attention to it, because details determine success or failure

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

SDS of cas: 3194-15-8. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: 1-(Furan-2-yl)propan-1-one, is researched, Molecular C7H8O2, CAS is 3194-15-8, about Effect of thermal treatment on the flavor generation from Maillard reaction of xylose and chicken peptide. Author is Liu, Jianbin; Liu, Mengya; He, Congcong; Song, Huanlu; Chen, Feng.

In this research, effect of the thermal treatment on the flavor generation from Maillard reaction of xylose and chicken peptide was studied. In summary, high temperature (>100 °C) could remarkably increase the formation of meaty aroma generated by xylose and chicken peptide through a Maillard reaction system, while lower temperature and longer heating tended to generate a broth-like taste (i.e., umami and kokumi). Pyrazines were the major contributors to the nutty/roast and basic meaty aroma in the Maillard reaction products (MRP), while the Glu released under the low temperature heating was considered an important contributor to the umami taste of MRPs. The low mol. weight peptide (<500 Da) was considered as the main contributor of the generation of pyrazines and 2-furfurylpyrrole, which could be due to the high reaction activity of the amidogen in these compounds In addition, crosslinking compounds with mol. weight >1000 Da formed from peptides <500 Da in the low temperature heating might be involved in formation of important kokumi-active compounds, while the high mol. compounds MRPs >3000 Da were very likely responsible for the bitter taste.

The article 《Effect of thermal treatment on the flavor generation from Maillard reaction of xylose and chicken peptide》 also mentions many details about this compound(3194-15-8)SDS of cas: 3194-15-8, you can pay attention to it, because details determine success or failure

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Journal of Chromatography A called Elucidation of the aroma compositions of Zhenjiang aromatic vinegar using comprehensive two dimensional gas chromatography coupled to time-of-flight mass spectrometry and gas chromatography-olfactometry, Author is Zhou, Zhilei; Liu, Shuangping; Kong, Xiangwei; Ji, Zhongwei; Han, Xiao; Wu, Jianfeng; Mao, Jian, which mentions a compound: 3194-15-8, SMILESS is O=C(C1=CC=CO1)CC, Molecular C7H8O2, Computed Properties of C7H8O2.

In this work, a method to characterize the aroma compounds of Zhenjiang aromatic vinegar (ZAV) was developed using comprehensive two dimensional gas chromatog. (GC × GC) coupled with time-of-flight mass spectrometry (TOFMS) and gas chromatog. olfactometry (GC-O). The column combination was optimized and good separation was achieved. Structured chromatograms of furans and pyrazines were obtained and discussed. A total of 360 compounds were tentatively identified based on mass spectrum match factors, structured chromatogram and linear retention indexes comparison. The most abundant class in number was ketones. A large number of esters, furans and derivatives, aldehydes and alcs. were also detected. The odor-active components were identified by comparison of the reported odor of the identified compounds with the odor of corresponding GC-O region. The odorants of methanethiol, 2-methyl-propanal, 2-methyl-butanal/3-methyl-butanal, octanal, 1-octen-3-one, di-Me trisulfide, trimethyl-pyrazine, acetic acid, 3-(methylthio)-propanal, furfural, benzeneacetaldehyde, 3-methyl-butanoic acid/2-methyl-butanoic acid and phenethyl acetate were suspected to be the most potent. About half of them were identified as significant aroma constituents in ZAV for the first time. Their contribution to specific sensory attribute of ZAJ was also studied. The results indicated that the presented method is suitable for characterization of ZAV aroma constituents. This study also enriches our knowledge on the components and aroma of ZAV.

Different reactions of this compound(1-(Furan-2-yl)propan-1-one)Computed Properties of C7H8O2 require different conditions, so the reaction conditions are very important.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Action of mixed organomagnesium compounds on N-disubstituted amides of α-furoic acid》. Authors are Maxim, N.; Zugravescu, I.; Fulga, I..The article about the compound:1-(Furan-2-yl)propan-1-onecas:3194-15-8,SMILESS:O=C(C1=CC=CO1)CC).Category: benzoxazole. Through the article, more information about this compound (cas:3194-15-8) is conveyed.

In aromatic series of keto amides, BzNR2, the action of the Grignard reagent produces ketones except in the instance of BzNEt2, where PhMgBr gave in addition Ph3CNEtPh (Busch and Fleischmann, C. A. 4, 3237). The action of the Grignard reagent has been studied on furoylanilides prepared by the action of α- furoyl chloride (I) on PhNHMe, PhNHEt and Ph2NH. A mixture of 136 g. PhNHMe and 250 g. of anhydrous benzene was treated dropwise with 83 g. I. The filtered benzene solution was washed, dried and evaporated and the crude product was recrystallized from benzene or alc., yielding 90% of α-furoyl-N-methylanilide (II), C12H11NO2, m. 120°. Similarly were prepared the corresponding ethylanilide (III), m. 127°, and diphenylamide (IV), C17H13NO2, m. 157°, in 90 and 80% yields, resp. II (20 g.) was added portionwise with stirring to 35 g. EtMgBr in 160 g. Et2O and, after 12 h., the product was decomposed with 25% HCl. The Et2O layer yielded a crude product, b63 100-40°, which was washed with 30% HCl and extracted with Et2O, giving 4 g. of α- furyl Et ketone (V), b63 120°; semicarbazone, m. 172°. Treatment of II with iso-BuMgCl similarly gave α- furyl iso-Bu ketone (VI), b26 110°; semicarbazone, m. 174°. With III, EtMgBr and iso-BuMgCl gave only V and VI but the crude product obtained by the action of PhMgBr yielded α- furyl Ph ketone (VII), b25 197°, and the tertiary base, ethyl(furyldiphenylmethyl)aniline, C25H23NO, m. 181°. Treatment of III with o-MeC6H4MgBr gave the oily α- furyl o-tolyl ketone (VIII), C12H10O2, b22 177°. Similarly with IV, the Grignard reagents EtMgBr, iso-BuMgCl, o-MeC6H4MgBr and PhMgBr produced V, VI, VIII and VII. The behavior of the furyl series of keto amides is thus analogous to that of the aromatic series in every respect.

Different reactions of this compound(1-(Furan-2-yl)propan-1-one)Category: benzoxazole require different conditions, so the reaction conditions are very important.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem