483-76-1 | Page 5 of 10 | Heterocyclic Building Blocks-Benzoxazole

Razmjoo, Fatemeh’s team published research in Journal of Food Processing and Preservation in 2022-10-31 | CAS: 483-76-1

Fabrication and application of functional active packaging material based on carbohydrate biopolymers formulated with Lemon verbena/Ferulago angulata extracts for the preservation of raw chicken meat. Recommended basis is Cadinene. Products is: https://www.ambeed.com/products/189165-77-3.html, 51905-84-1

1. Trivial name: delta-Cadinene.
2. It’s mainly derived from flue-cured tobacco, burley tobacco and flavoured tobacco, it has a strong aroma and a good fixing effect, suitable for perfume, cosmetics, can also be used in wine, cigarettes, and toothpaste.
. Recommended Products is: 29350-73-0 and 51905-84-1.

In this research using Zedo gum (ZG) and CM-cellulose (CMC) as well as Lemon and Ferulago extracts (LVE/FAE) new active packaging was designed. Biodegradable films with five various proportions of ZG to CMC were made by applying the casting process. The incorporation of LVE or FAE into CMC/ZG composite films significantly reduced moisture content (MC) and water vapor permeability (WVP). The tensile strength increased from 6.92 (MPa) for CMC/ZG film to 11.51 MPa for CMC/ZG/2.5¦Ìl LVE and FAE film; as well as elongation at break decreased from 24.21% for CMC/ZG film to 6.10% for CMC/ZG/2.5¦Ìl LVE and FAE film. In conclusion, the 20:80 proportion of ZG/CMC along with 2.5¦Ìl LVE and FAE can be used as the best ratio for mech. properties, moisture content, and permeability compared to the CMC/ZG film with individual FAE or LVE and can be a good source for making edible films. Novelty impact statement : The most important novelty is related to using of Lemon verbena and Ferulago angulata extracts in the combination of Zedo gum and CM-cellulose. Producing active packaging with Lemon verbena and Ferulago angulata extracts in polymer matric. Increasing the shelf life of compounds such as raw chicken meat with active packaging.

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Liang, Lu’s team published research in LWT–Food Science and Technology in 2022-09-15 | CAS: 483-76-1

Untargeted metabolomics analysis based on HS-SPME-GC-MS and UPLC-Q-TOF/MS reveals the contribution of stem to the flavor of Cyclocarya paliurus herbal extract. Recommended basis is Cadinene. Products is: https://www.ambeed.com/products/189165-77-3.html, 51905-84-1

The herbal tea made from the leaves and stems of Cyclocarya paliurus is thought to be more flavorful than those made from the leaves only. However, evidence supporting this view is not available yet. 53 VOCs and 54 non-VOCs were identified via HS-SPME-GC-MS and UPLC-Q-TOF/MS, resp., which were found to vary dramatically in three groups of samples (combination of stems and leaves, separated leaves, and separated stems). 11 VOCs and 18 non-VOCs potential markers are responsible for the change of metabolic effects through the biosynthesis of flavonoids, the synthesis of terpenoids, and the oxidation of fatty acids and carotenoids. In response, the stems were effective to enhance fatty odors, the initial astringency and bitterness and the aftertaste of sweetness of the leaves. Stems are conducive to increasing total phenolic content, total flavonoid content and antioxidant capacity of Cyclocarya paliurus herbal extract because of the increase in polyphenols. In addition, the stems have the potential to be used as raw materials for nerolidol and polyphenols extraction This study has been the first to determine the contribution of stem to the flavor of Cyclocarya paliurus herbal tea and these results provide the theor. basis for making Cyclocarya paliurus herbal tea with stems.

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Alimi, Dhouha’s team published research in Waste and Biomass Valorization in 2022-10-31 | CAS: 483-76-1

Valorization of Volatile Oils and Some Crude Extracts from the Tunisian Plants Juniperus communis and Origanum majorana for the Control of Hyalomma scupense (Acari: Ixodidae). Recommended basis is Cadinene. Products is: https://www.ambeed.com/products/189165-77-3.html, 51905-84-1

This investigation tested the in vitro acaricidal activity of essential oils and raw extracts of Juniperus communis and Origanum majorana compared with the synthetic acaricide amitraz against various stage of Hyalomma scupense cattle tick. The hydrodistilation technique was used to extract essential oils, while chem. components in the plants were obtained using solvents of increasing polarity (hexane, Et acetate and methanol). The evaluation on H. scupense was performed with the adult immersion test at concentrations ranging from 1.25 to 10 mg/mL and the larval packet test from 0.625 to 10 mg/mL. Qual. anal. of J. communis essential oil showed ¦Á-pinene (52.31%), ¦Ä 3-carene (12.77%), ¦Â-phellandrene (7.60%), 1,8 cineole (6.95%) and ¦Á-terpinenyl acetate (6.58%) as the major chem. components. O. majorana oil was mainly composed of 4-terpineol (23.05%), Cis-Thujan-4-ol (18.30%), ¦Ä-terpinene (13.61%), ¦Á-terpinene (9.16%) and sabinene (7.96%). In adult immersion test, J. communis essential oil, at 10 mg/mL concentration exhibited strong acaricidal efficacy and reproductive inhibitory effects on treated ticks (100%) than O. majorana oil (91.95%). In larval packet test, J. communis oil had 100% mortality at 10 mg/mL, 24 h of exposure, whereas O. majorana oil had 90.64% mortality of H. scupense larvae. J. communis essential oil showed greater efficacy than all tested extracts and amitraz on both female adults and larvae of H. scupense. Quant. anal. showed that J. communis methanolic extract had the greatest ability to extract such phenolic compounds, with a total phenol content of 188.17 (mg gallic acid equivalent/g dry weight) and also had the highest acaricidal activity against engorged females and larvae of H. scupense with LC50 values of 2.46 and 4.12 mg/mL, resp. The results showed that both plants, particularly J. communis considered as potential candidates for biocontrol of H. scupense in the field.

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Yang, Yanqin’s team published research in Food Chemistry in 2022-09-01 | CAS: 483-76-1

Insight into aroma dynamic changes during the whole manufacturing process of chestnut-like aroma green tea by combining GC-E-Nose, GC-IMS, and GC x GC-TOFMS. Recommended basis is Cadinene. Products is: https://www.ambeed.com/products/189165-77-3.html, 51905-84-1

Processing is the crucial factor for green tea aroma quality. In this study, the aroma dynamic changes throughout the manufacturing process of chestnut-like aroma green tea were investigated with gas chromatog. electronic nose (GC-E-Nose), gas chromatog.-ion mobility spectrometry (GC-IMS), and comprehensive two-dimensional gas chromatog. coupled to time-of-flight mass spectrometry (GC x GC-TOFMS). GC-IMS identified 33 volatile compounds while GC x GC-TOFMS identified 211 volatile components. Drying exerted the greatest influence on the volatile components of chestnut-like aroma green tea, and promoted the generation of heterocyclic compounds and sulfur compounds which were commonly generated via the Maillard reaction during the roasting stage. A large number of heterocyclic compounds such as 1-methyl-1H-pyrrole, pyrrole, methylpyrazine, furfural, 2-ethyl-5-methylpyrazine, 1-ethyl-1H-pyrrole-2-carboxaldehyde, and 3-acetylpyrrole were newly formed during the drying process. This study also validated the suitability of GC-E-Nose combined with GC-IMS and GC x GC-TOFMS for tracking the changes in volatile components of green tea throughout the manufacturing process.

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Chac, Le D.’s team published research in Chemistry of Natural Compounds in 2022-07-31 | CAS: 483-76-1

Chemical Composition and Antifungal Activity of Essential Oil from the Roots of Tinomiscium petiolare. Recommended basis is Cadinene. Products is: https://www.ambeed.com/products/189165-77-3.html, 51905-84-1

Tinomiscium petiolare Hook. f. & Thomson is a medicinal species of the genus Tinomiscium (Menispermaceae). This species grows naturally in mixed forests at an altitude of 200 to 600 m in tropical Asian countries, including Vietnam. The literature search has not revealed any reports of the chem. composition and antifungal activity of the root oils of T. petiolare. The average yield of the essential oil was 0.05% ¡À 0.01 (v/w) calculated on a dry weight basis. In addition, significant quantities of ¦Ã-terpinene (5.50%), ¦Â-bisabolene (5.07%), geraniol (4.82%), geranyl acetate (4.70%), and (Z)-ligustilide (4.45%) were also present in the oil. This is to our knowledge the first report on the chem. composition of T. petiolare root oil. Results show that the root oil of T. petiolare inhibited the growth of Aspergillus niger with an MIC value of 200 ¦Ì g/mL. The antifungal activity of essential oil can be explained by the presence of geranial and neral.

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Nasri, Chaimae’s team published research in Biocatalysis and Agricultural Biotechnology in 2022-09-30 | CAS: 483-76-1

Seven Persea americana varieties essential oils comparison: Chemical composition, toxicity, antibacterial, and antioxidant activities. Recommended basis is Cadinene. Products is: https://www.ambeed.com/products/189165-77-3.html, 51905-84-1

The present study aims at comparing the chem. composition of seven varieties of Persea americana leaves essential oils and at evaluating some of its activities such as antibacterial activity, antioxidant activity and acute toxicity. The results showed strong variations in the volatile compounds present in some of the studied oils from these varieties. Estragol was the major component of Ettinger (30.04%) and Fuerte (36.74%) leaf essential oils and is absent from four varieties. Regarding the EO of Hass, Bacon and Maluma Hass, the 2-(8Z,11Z)-8,11-heptadecadienyl-furan was the main volatile compound (67,37%, 43.61% and 59.9% resp.) while Caryophyllene was the main substance in the leaf EO of Reed (36.61%) and Zutano (17.68%) varieties. Concerning the acute toxicity test of these essential oils, the results obtained showed that the LD (LD50) is higher than 2000 mg/kg for EO of Maluma Hass, Reed and Ettinger varieties, whereas it is greater than 300 mg/kg for those of Zutano, Bacon, Hass and Fuerte. The study of antioxidant and antibacterial activities revealed promising values against gram-pos. bacteria (Staphylococcus epidermidis, Staphylococcus aureus) and an encouraging antioxidant power. Based on these results, it appears that avocado leaf essential oils are in fact a potential source of bioactive phytochems. for medical and cosmetic use, and could also be considered as the first report on Persea americana grown in Morocco.

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Karacelik, Ayca Aktas’s team published research in Chemistry & Biodiversity in 2022-10-31 | CAS: 483-76-1

Phytochemical Composition and Biological Activities of Angelica sylvestris L. var. stenoptera Ave-Lall ex Boiss.: An Endangered Medicinal Plant of Northeast Turkey. Recommended basis is Cadinene. Products is: https://www.ambeed.com/products/189165-77-3.html, 51905-84-1

Angelica sylvestris L. var. stenoptera Ave-Lall ex Boiss. (ASS) is an endangered endemic plant to Turkey. The objective of the study was to determine antioxidant activities, total phenolics, and phytochem. properties of methanolic extracts (MEs) and essential oil (EO) from ASS for the first time with the methods of 2,2-diphenyl-1-picrylhydrazyl (DPPH¡¤) radical scavenging activities, 2,2-azinobis(3-ethylbenzothiazoline-6-sulfonic acid (ABTS¡¤+), ferric reducing/antioxidant power (FRAP), the Folin-Ciocalteu, liquid chromatog.-tandem mass spectrometry (LC-MS/MS), and gas chromatog.-mass spectrometry (GC-MS), resp. The leaf extract of ASS was found to be the richest in phenolic content (543.91¡À6.33 GAE, ¦Ìg/mL) and showed the highest DPPH¡¤ and FRAP activities (IC50: 0.1140¡À0.0011 mg/mL, 675.62¡À15.01 ¦ÌM TEAC). EO of ASS root showed DPPH¡¤ and FRAP activities (IC50: 1.3248¡À0.0572 mg/mL, 346.67¡À12.75 ¦ÌM TEAC). 19 phenolics were detected in MEs of different parts of ASS by LC/MS/MS. In the chem. composition of ASS root EO by GC/MS, globulol (70.70 %) was found to be the major compound Our results indicate that ASS can be used a source of phytochems. and antioxidants for conservation and sustainability of endangered plants.

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Zimmermann, Rubens Candido’s team published research in Industrial Crops and Products in 2022-08-31 | CAS: 483-76-1

Insecticidal and antifungal activities of Melaleuca rhaphiophylla essential oil against insects and seed-borne pathogens in stored products. Recommended basis is Cadinene. Products is: https://www.ambeed.com/products/189165-77-3.html, 51905-84-1

Essential oils (EOs) are substances with biol. properties that can be used to inhibit insects and fungi in storage systems. The EOs from plants of the genus Melaleuca (Myrtaceae) show insecticidal and antifungal activities. However, so far, there are no reports regarding Melaleuca rhaphiophylla (Myrtaceae) EO. Therefore, we sought to investigate the insecticidal and antifungal activities of M. rhaphiophylla EO against storage pests and fungi. The plant’s EO was extracted in a vat using the steam drag method and analyzed by gas chromatog.-mass spectrometry. The insecticidal effect against Sitophilus zeamais and Sitophilus oryzae (Coleoptera: Curculionidae) was evaluated through contact and fumigation methods in order to select the optimized exposure route. Then, the lethal concentration (LC), lethal time (LT), and mean survival time (MST) were estimated Antifungal activity against Aspergillus flavus, Aspergillus niger, Aspergillus nomius and Fusarium graminearum was tested through volatilization and direct contact. Twenty-two compounds were identified in the chem. composition of M. rhaphiophylla EO and the major compounds were ¦Á-terpinene (6.46%), 1,8-cineole (11.54%), ¦Ã-terpinene (13.2%), terpinolene (28.72%) and terpinen-4-ol (19.82%). The fumigation method of application caused the highest mortality in both insects. The values for LC50 (90.55 and 72.88 of substance L-1 of air), LT50 (0.92 and 1.23 h) and MST (92.17 and 92.67 h) were similar between species (S. zeamais and S. oryzae, resp.). The volatilization method showed low fungicidal activity (< 30% of inhibition) against all isolates. The contact method showed an inhibition greater than 90%with higher toxicity for Aspergillus. Our results showed that M. rhaphiophylla EO has potential as an alternative product to control storage pests and fungi. Insecticidal and antifungal activities of Melaleuca rhaphiophylla essential oil against insects and seed-borne pathogens in stored products. Recommended basis is Cadinene. Products is: https://www.ambeed.com/products/189165-77-3.html, 51905-84-1

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Alsabte, Ahmed’s team published research in Phytoparasitica in 2022-07-31 | CAS: 483-76-1

Effects of Volatile Organic Compounds (VOCs) emitted by citrus infested with Aonidiella aurantii on the predator Rhyzobius lophanthae attraction. Recommended basis is Cadinene. Products is: https://www.ambeed.com/products/189165-77-3.html, 51905-84-1

This study identifies the volatile organic compounds (VOCs) emitted by citrus when infested with California red scale (Aonidiella aurantii) and determines which of these elicit behavior responses in the predator Rhyzobius lophanthae. Headspace solid-phase micro extractions (HS-SPME) technique combined with gas chromatog.-mass spectrometry (GC-MS) was used to identify compounds and Y-tube olfactometer to determine R. lophanthae behavior responses. According to the results, 22 VOCs were detected in infested citrus plants and some of them were increased in lemon, orange and tangerine by A. aurantii infestation. R. lophanthae individuals were attracted to infested citrus saplings. According to bioassays with the olfactometer, they were attracted to Me salicylate and D-limonene at dosages of 1 and 10¦ÌL/mL by using a Y-tube olfactometer. These results explain how citrus volatiles can affect the response of the predator R. lophanthae.

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Li, Yan-Nan’s team published research in Food Control in 2022-07-31 | CAS: 483-76-1

Linalool, the main volatile constituent from Zanthoxylum schinifolium pericarp, prevents growth of Aspergillus flavus in post-harvest grains. Recommended basis is Cadinene. Products is: https://www.ambeed.com/products/189165-77-3.html, 51905-84-1

Plant volatile organic compounds (PVOCs) have shown great potential as alternatives to synthetic insecticides or fungicides for stored grain management. Zanthoxylum schinifolium pericarp, a traditional Chinese spice, is conventionally buried in grain piles to prevent fungal spoilage of stored grains in China. However, the chem. basis and antifungal mechanism of PVOCs from Z. schinifolium pericarp by which they inhibit spoilage remain unclear. In this study, the effectiveness of PVOCs from Z. schinifolium pericarp against Aspergillus flavus growth in high-moisture wheat grains was studied under simulated storage conditions. The growth of A. flavus in the grains was inhibited in a dose-dependent manner. The chem. composition of PVOCs from Z. schinifolium pericarp was determined using gas chromatog.-mass spectrometry; linalool (50.31%) and D-limonene (20.92%) were the two main components. An antifungal experiment showed that 0.571 and 1.2 ¦ÌL/mL concentrations of linalool completely inhibited A. flavus growth upon vapor and liquid contact, resp. D-limonene showed much lower antifungal activity, indicating that linalool is responsible for the antifungal activity of PVOCs from Z. schinifolium pericarp. Linalool treatment disrupted the cell membrane of A. flavus, resulting in increased electrolyte leakage and A260nm in the culture supernatant. After 6 h of exposure to 1.2 ¦ÌL/mL linalool, metabolomic anal. revealed 90 differentially expressed metabolites in A. flavus mycelia, including 69 upregulated and 21 downregulated metabolites. It was speculated that linalool inhibited A. flavus by disrupting the permeability and integrity of cell membranes, tricarboxylic acid cycle, and ATP binding cassette transport and by inducing mitochondrial dysfunction and oxidative stress. This study shows the potential of PVOCs from Z. schinifolium pericarp as biofumigants for stored grain management and provides a new perspective on their antifungal mechanism against A. flavus growth.

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem