New discoveries in chemical research and development in 2021. The transformation of simple hydrocarbons into more complex and valuable products has revolutionised modern synthetic chemistry. In an article, author is Wang, Wei, once mentioned the application of 504-02-9, HPLC of Formula: https://www.ambeed.com/products/504-02-9.html, Name is Cyclohexane-1,3-dione, molecular formula is C6H8O2, molecular weight is 112.13, category is benzoxazole. Now introduce a scientific discovery about this category.
A facile and efficient method for construction of S-CF2 or O-CF2 bonds through intermolecular radical nucleophilic substitution (S(RN)1) reaction of 2-bromo-2,2-difluoro-N-phenylacetamide and thiophenols or phenols was developed, which has also been successfully utilized in the intramolecular S(RN)1 reaction to generate a new O-CF2 bonds for synthesis of biologically important 2,2-difluoro-2H-benzo [1,4]oxazin-3-one. The protocol enables an efficient access to gem-difluoromethylene-containing thioethers or ethers and oxazin heterocycles with good to excellent yields by inter/intramolecular radical nucleophilic substitution reaction under mild reaction conditions. (C) 2020 Elsevier Ltd. All rights reserved.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 504-02-9. HPLC of Formula: https://www.ambeed.com/products/504-02-9.html.
Reference:
Benzoxazole – Wikipedia,
,Benzoxazole | C7H5NO – PubChem