Category: 5676-58-4

Correlation of N.M.R. chemical shifts of 2-methyl protons of substituted benzazoles with Hammett’s substituents constants was written by Modica, Gaetano Di;Barni, Ermanno;Gasco, Alberto. And the article was included in Journal of Heterocyclic Chemistry in 1965.Recommanded Product: 2,5-Dimethylbenzoxazole This article mentions the following:

The chem. shifts of 2-methyl protons of twenty-one 5- and 6-substituted benzazoles determined in carbon tetrachloride solution, were plotted against the Hammett substituent constants using σ_m for groups in the 5- position and σ_p for groups in the 6-position, obtaining satisfactory linear correlations. These results are taken to indicate that electronic effects are transmitted to the 2-position predominantly through the N atom and that virtually no transmission occurs through the hetero atom. The deshielding effect of the hetero atom is opposite to the electronegativity and this may be qual. explained in terms of different aromaticity of these heterocycles. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Recommanded Product: 2,5-Dimethylbenzoxazole).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Being a heterocyclic compound, benzoxazole finds use in research as a starting material for the synthesis of larger, usually bioactive structures. It is found within the chemical structures of pharmaceutical drugs such as flunoxaprofen and tafamidis.Recommanded Product: 2,5-Dimethylbenzoxazole

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

One-pot synthesis of benzoxazoles via the metal-free ortho-C-H functionalization of phenols with nitroalkanes was written by Aksenov, Nicolai A.;Aksenov, Alexander V.;Nadein, Oleg N.;Aksenov, Dmitrii A.;Smirnov, Alexander N.;Rubin, Michael. And the article was included in RSC Advances in 2015.Recommanded Product: 2,5-Dimethylbenzoxazole This article mentions the following:

A one-pot cascade transformation involving metal-free and oxidant-free direct ortho-C-H functionalization, followed by Beckman rearrangement and intramol. cyclocondensation to produce benzoxazoles I [R¹ = H, Me, Et, i-Pr, OH; R² = H, Me, OH, F; R³ = H, Me; R⁴ = CH₃, CH₂CH₃, (CH₂)₄CH₃, C₆H₅, C₆H₅CH₂] and benzobisoxazoles II (R⁵ = CH₃, C₆H₅CH₂; R⁶ = H, Me) directly from easily available phenols and PPA-activated nitroalkanes. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Recommanded Product: 2,5-Dimethylbenzoxazole).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazole nucleus is one of the most important heterocyclic compounds exhibiting remarkable pharmacological activities. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as antibacterial, antifungal, anticancer.Recommanded Product: 2,5-Dimethylbenzoxazole

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Reaction of oximes of 2-hydroxyacetophenone, chalcone, flavanone, and flavone was written by Bagade, M. B.;Ghiya, B. J.. And the article was included in Asian Journal of Chemistry in 1991.SDS of cas: 5676-58-4 This article mentions the following:

Oximes of 2-hydroxyacetophenone, chalcone, flavanone, and flavone were prepared by the action of hydroxylamine hydrochloride on the resp. compounds The oximes gave back the starting material by the action of HCl, nitrous acid or CrO₃ in AcOH. 2-Hydroxy-5-methylacetophenone oxime (I), with POCl₃, cyclized to give benzoxazole II. I also condensed with RCHO (R = Ph, 4-MeOC₆H₄) to give chalcone oxime III. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4SDS of cas: 5676-58-4).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazoles belong to the group of well-known antifungal agents with antioxidant, antiallergic, antitumoral and antiparasitic activity. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as antibacterial, antifungal, anticancer.SDS of cas: 5676-58-4

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Regioselective Syntheses of 2- and 4-Formylpyrido[2,1-b]benzoxazoles was written by Li, Ke-Lai;Du, Zong-Bo;Guo, Can-Cheng;Chen, Qing-Yun. And the article was included in Journal of Organic Chemistry in 2009.Electric Literature of C9H9NO This article mentions the following:

O-Acetaminophenols I (R = H, Cl, Me, t-Bu, NO₂, OMe, Ph) reacted with Vilsmeier reagent under Meth-Cohn conditions to yield 2-formylpyrido[2,1-b]benzoxazoles II unexpectedly besides the known compounds III. Refluxing III in acetic anhydride gave 4-formylpyrido[2,1-b]benzoxazoles IV, the regioisomers of II. II (R = H) and IV (R = H) were structurally characterized by X-ray crystallog. A mechanism for the formation of II involving sequential chlorination, dimerization, intramol. elimination of HCl to form the oxazole ring, formylation twice, and regioselective intramol. nucleophilic cyclization to construct the pyridone ring is proposed. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Electric Literature of C9H9NO).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazoles belong to the group of well-known antifungal agents with antioxidant, antiallergic, antitumoral and antiparasitic activity. It is found within the chemical structures of pharmaceutical drugs such as flunoxaprofen and tafamidis.Electric Literature of C9H9NO

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Aggregation of unsymmetrical anionic carbocyanine. I. Preparation and aggregation of sodium salt of 1′-ethyl-3,3′-bis-(3-sulfopropyl)-5-methoxy-5′,6′-dichlorobenzimidazolooxacarbocyanine was written by Huang, Guangtuan;Lu, Minghu;Huang, Deyin. And the article was included in Huadong Ligong Daxue Xuebao in 1998.Name: 2,5-Dimethylbenzoxazole This article mentions the following:

The anionic carbocyanine dye, sodium salt of 1′-ethyl-3, 3′-bis-(3-sulfopropyl)-5-methoxy-5′,6′-dichloro-benzimidazolo-oxa-carbocyanine and its intermediates were synthesized. Its structure has been characterized by IR, ¹H-NMR and MS. UV-Vis spectra of this dye in Me alc., water, 1,2-dichloroethane, chlorobenzene and bromobenzene have been determined This dye could not form J-aggregate when its concentration was 1 x 10^-5 mol/L in Me alc. and water. When it was dissolved in 1,2-dichloroethane, chlorobenzene and bromobenzene, it tended to form J-aggregate. The process of aggregation has also been studied for the solution of this dye dissolved in chloroform. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Name: 2,5-Dimethylbenzoxazole).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazole derivatives have different biological activities. A number of marketed drugs are available having benzoxazole as core active moiety like, nonsteroidal anti-inflammatory drug (NSAID)—flunoxaprofen, benoxaprofen, antibiotic—calcimycin.Name: 2,5-Dimethylbenzoxazole

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Research on benzoxazole compounds. I. Synthesis and photophysical properties was written by Shen, Yongjia;Ren, Shengwu;Wang, Bingkui. And the article was included in Huadong Huagong Xueyuan Xuebao in 1990.SDS of cas: 5676-58-4 This article mentions the following:

Benzoxazoles I (R = H, Me, Cl, Ph; Z = CH:CHC₆H₄, CH:CHC₆H₄CH:CH, C₆H₄CH:CHC₆H₄) and II (R¹ = H, Me, Cl) were prepared E.g. condensation of 2-HOC₆H₄NH₂ with 4-(ClCO)C₆H₄CH:CHCOCl gave I (R = H, Z = CH:CHC₆H₄). IR, UV, fluorescence, and laser emission spectra of I–II were reported. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4SDS of cas: 5676-58-4).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazole derivatives have gained a lot of importance in the past few years because of their use in intermediates for the preparation of new biological materials. It is found within the chemical structures of pharmaceutical drugs such as flunoxaprofen and tafamidis.SDS of cas: 5676-58-4

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Sodium dichloroiodate promoted C-C bond cleavage: An efficient synthesis of 1,3-benzazoles via condensation of o-amino/mercapto/hydroxyanilines with β-diketones was written by Bhagat, Saket B.;Ghodse, Shrikant M.;Telvekar, Vikas N.. And the article was included in Journal of Chemical Sciences (Berlin, Germany) in 2018.Electric Literature of C9H9NO This article mentions the following:

An efficient aqueous sodium dichloroiodate (NaICl₂) mediated protocol is developed for the synthesis of benzo-fused azoles I (R¹ = H, Me, Cl; R² = Me, Et, i-Pr, Ph; X = NH, O, S) by the cyclization of 2-amino-substituted anilines, thiophenols or phenols 2-HX-5-R¹C₆H₃NH₂ with β-diketone compounds R²C(O)CH₂C(O)R³ (R³ = Me, Et, i-Pr, Ph). The reactions gave moderate to good yield of the corresponding 2-substituted benzimidazoles, benzothiazoles or benzoxazoles, resp., under mild conditions. This tandem process involved a C-C bond cleavage and C-N bond formation. The reaction provides a rapid access to 1,3-benzazoles I in good yields, thus speeding up the drug discovery process. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Electric Literature of C9H9NO).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Being a heterocyclic compound, benzoxazole finds use in research as a starting material for the synthesis of larger, usually bioactive structures. In the past years, numerous benzoxazole derivatives have been synthesised and evaluated for their biological potential.Electric Literature of C9H9NO

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Infrared spectrum of tetrafluorohydrazine was written by Durig, J. R.;Lord, R. C.. And the article was included in Spectrochimica Acta in 1963.Related Products of 5676-58-4 This article mentions the following:

The infrared spectrum of tetrafluorohydrazine was recorded and a complete vibrational analysis carried out on the assumption that the mol. belongs to the point group C₂. The 12 normal vibra tions of this point group were assigned to observed bands. The band due to the torsional vibration was observed at 122 cm.^-1 in the far infrared spectrum of the vapor. The band contours are consistent with a dihedral angle <90°. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Related Products of 5676-58-4).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazole derivatives have gained a lot of importance in the past few years because of their use in intermediates for the preparation of new biological materials. In the past years, numerous benzoxazole derivatives have been synthesised and evaluated for their biological potential.Related Products of 5676-58-4

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Eco-friendly syntheses of 2-substituted benzoxazoles and 2-substituted benzothiazoles from 2-aminophenols, 2-aminothiophenols and DMF derivatives in the presence of imidazolium chloride was written by Tian, Qingqiang;Luo, Wen;Gan, Zongjie;Li, Dan;Dai, Zeshu;Wang, Huajun;Wang, Xuetong;Yuan, Jianyong. And the article was included in Molecules in 2019.SDS of cas: 5676-58-4 This article mentions the following:

A simple, economical and metal-free approach to the synthesis of 2-substituted benzoxazoles/benzothiazoles I (R = H, 6-Me, 5-Cl, 6-NO₂, etc.; R¹ = Me, Ph, pyridin-2-yl, 3-oxo-3-phenylpropyl, etc.; X = O, S) in moderate to excellent yields from 2-aminophenols/2-aminothiophenols R²-2-NH₂C₆H₃XH (R² = H, 5-Me, 4-Cl, 5-NO₂, etc.) and DMF derivatives, only using imidazolium chloride (50% mmol) as promoter without any other additive, was reported. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4SDS of cas: 5676-58-4).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. The benzoxazole moiety is widely found in various natural compounds, which are often found to be biologically active. A number of marketed drugs are available having benzoxazole as core active moiety like, nonsteroidal anti-inflammatory drug (NSAID)—flunoxaprofen, benoxaprofen, antibiotic—calcimycin.SDS of cas: 5676-58-4

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Synthesis of cyanine dyes and investigation of their in vitro antiprotozoal activities was written by Ge, Jian-Feng;Zhang, Qian-Qian;Lu, Jian-Mei;Kaiser, Marcel;Wittlin, Sergio;Brun, Reto;Ihara, Masataka. And the article was included in MedChemComm in 2012.Electric Literature of C9H9NO This article mentions the following:

Six cyanine dyes (including sym. and unsym. trimethine and pentamethine cyanine dyes with substituted benzoxazolyl or benzothiazolyl groups), were synthesized and evaluated for their in-vitro antiprotozoal activities against Plasmodium falciparum K1, Trypanosoma cruzi, Trypanosoma brucei rhodesiense and Leishmania donovani. Several trimethine cyanine dyes containing benzothiazole groups exhibited strong activity against Plasmodium falciparum and Trypanosoma cruzi, while one sym. pentamethine cyanine containing a fluorinated benzothiazolyl group was highly active against Trypanosoma brucei rhodesiense. The title compounds thus formed included a benzothiazole-benzothiazolium derivative (I) [[(benzothiazolylidene)pentadienyl]benzothiazolium salt, pentamethine compound] and related compounds and benzoxazole analogs. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Electric Literature of C9H9NO).

2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazole derivatives have gained a lot of importance in the past few years because of their use in intermediates for the preparation of new biological materials. A number of marketed drugs are available having benzoxazole as core active moiety like, nonsteroidal anti-inflammatory drug (NSAID)—flunoxaprofen, benoxaprofen, antibiotic—calcimycin.Electric Literature of C9H9NO

Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem