Category: 64037-07-6

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TRICYCLIC PI3K INHIBITOR COMPOUNDS AND METHODS OF USE

Described herein are tricyclic compounds with phosphoinositide-3 kinase (PI3K) modulation activity or function having the Formula I structure: or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I compounds, as well as methods of using such PI3K modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon PI3K dysregulation.

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Reference£º
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

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(1aR,12bS)-8-cyclohexyl-11-fluoro-N-((1-methylcyclopropyl)sulfonyl)-1a-((3-methyl-3,8-diazabicyclo[3.2.1]oct-8-yl)carbonyl)-1,1a,2,2b-tetrahydrocyclopropa[d]indolo[2,1-a][2]benzazepine-5-carboxamide for use in treating HCV

The invention relates to an administration unit comprising a compound of formula and/or pharmaceutically acceptable salts thereof, and to a packaging comprising the administration unit according to the invention.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 64037-07-6

Reference£º
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Application of 64037-07-6, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.64037-07-6, Name is 5-Bromobenzo[d]oxazol-2-amine, molecular formula is C7H5BrN2O. In a Patent£¬once mentioned of 64037-07-6

Substituted benzo – 1, 3 – […] compound, its preparation and use (by machine translation)

The invention relates to the general formula I shown substituted benzo – 1, 3 – […] compound, the invention also relates to the preparation of the compounds and method for preparing the anti tubercular drug use. The compounds of this invention not only sensitive strains of Mycobacterium tuberculosis, but also right isoniazid and rifampicin equality of traditional anti-tuberculosis drugs have the drug resistance of the drug resistant bacterial strain, is very wide application foreground model anti-Mycobacterium tuberculosis compound. (by machine translation)

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Reference£º
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Reference of 64037-07-6, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.64037-07-6, Name is 5-Bromobenzo[d]oxazol-2-amine, molecular formula is C7H5BrN2O. In a Patent£¬once mentioned of 64037-07-6

Enhanced treatment regimens using mTor inhibitors

The present invention provides for methods and pharmaceutical compositions comprising inhibitors of mTorC1 and/or mTorC2. In some aspects, the invention provides for treatment regimens resulting in enhanced treatment efficacy and better tolerability.

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Reference£º
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

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Preventive and/or therapeutic agent of immune disease

Provided is a preventive and/or therapeutic agent for immune diseases containing a compound having a BTK inhibitory activity or a salt thereof, as an active ingredient. A preventive and/or therapeutic agent of immune diseases, comprising a compound represented by Formula (I), where R1 to R3, W, X, Y, Z, and n represent those as defined in the specification, or a salt thereof, as an active ingredient.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. category: benzoxazole, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 64037-07-6, in my other articles.

Reference£º
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

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BENZOXAZOLE KINASE INHIBITORS AND METHODS OF USE

The present invention provides chemical entities or compounds and pharmaceutical compositions thereof that are capable of modulating certain protein kinases such as mTor, tyrosine kinases, and/or lipid kinases such as PI3 kinase. Also provided in the present invention are methods of using these compositions to modulate activities of one or more of these kinases, especially for therapeutic applications.

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 64037-07-6, and how the biochemistry of the body works.Related Products of 64037-07-6

Reference£º
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Related Products of 64037-07-6, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 64037-07-6, Name is 5-Bromobenzo[d]oxazol-2-amine, molecular formula is C7H5BrN2O. In a Patent£¬once mentioned of 64037-07-6

METALLO-BETA-LACTAMASE INHIBITORS

The present invention relates to compounds of formula I that are metallo-beta-lactamase inhibitors, the synthesis of such compounds, and the use of such compounds for use with beta-lactam antibiotics for overcoming resistance.

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Reference£º
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

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Benzoxazole benzenesulfonamides as allosteric inhibitors of fructose-1,6-bisphosphatase

A series of novel benzoxazole benzenesulfonamides was synthesized as inhibitors of fructose-1,6-bisphosphatase (FBPase-1). Extensive SAR studies led to a potent inhibitor, 53, with an IC50 of 0.57 muM. Compound 17 exhibited excellent bioavailability and a good pharmacokinetic profile in rats.

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Reference£º
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Synthetic Route of 64037-07-6, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 64037-07-6, molcular formula is C7H5BrN2O, introducing its new discovery.

Electrochemical intramolecular c-h amination: Synthesis of benzoxazoles and benzothiazoles

A new method for metal-free intramolecular C-H amination has been developed. Electrochemical oxidation of 2-pyrimidyloxybenzenes and 2-pyrimidylthiobenzenes, which can be easily prepared from phenols and thiophenols, respectively, followed by the treatment of the resulting pyrimidinium ions with piperidine gives 2-aminobenzoxazoles and 2-aminobenzothiazoles, respectively.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 64037-07-6 is helpful to your research. Synthetic Route of 64037-07-6

Reference£º
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

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5 – Pyridyl -2 – amino – benzo [d] oxazole derivative and its preparation and use (by machine translation)

The present invention discloses the general formula (I) indicated by the 5 – pyridyl – 2 – amino – benzo [d] oxazole derivative or its pharmaceutically acceptable salt, its preparation method, pharmaceutical composition and use: According to the compounds of this invention can be used for preparing the treatment of cervical cancer, breast cancer, stomach cancer, liver cancer, renal carcinomas of the drug. (by machine translation)

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Reference£º
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem