77186-95-9, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. Benzo[d]oxazol-2-ylmethanol, cas is 77186-95-9,the benzoxazole compound, it is a common compound, a new synthetic route is introduced below.
2.98 g (20.0 mmol) of 2-hydroxymethylbenzoxazole, 2.23 g (22.0 mmol) of triethylamine, 0.04 g (0.6 mmol) of 3,5-di-tert-butyl-4-hydroxytoluene were added to a 100 ml recovery flask. 2 mmol) and tetrahydrofuran 40 ml were added to prepare a reaction solution.After the reaction solution was cooled to 0 C., 2.30 g (22.0 mmol) of methacryloyl chloride was added dropwise and the mixture was stirred at room temperature for 3 hours, and the precipitated triethylamine hydrochloride was filtered off. Subsequently, the reaction solution was concentrated, and the extracting operation with 20 ml of ethyl acetate was carried out three times, and the extracted solutions were mixed and concentrated to obtain 4.09 g of a yellow liquid (yield: 94%).
The chemical industry reduces the impact on the environment during synthesis,77186-95-9,Benzo[d]oxazol-2-ylmethanol,I believe this compound will play a more active role in future production and life.
Reference:
Patent; SHIKOKU CHEMICALS CORPORATION; OKUMURA, NAOTO; IKEDA, YUICHI; (27 pag.)JP2015/20962; (2015); A;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem