Category: benzoxazole

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole(SMILESS: FC1(F)OC2=CC=C(P(C3=CC=CC=C3)C4=CC=CC=C4)C(C5=C6OC(F)(F)OC6=CC=C5P(C7=CC=CC=C7)C8=CC=CC=C8)=C2O1,cas:503538-69-0) is researched.COA of Formula: C9H9NO. The article 《Iridium-Catalyzed Asymmetric Hydroalkenylation of Norbornene Derivatives》 in relation to this compound, is published in Organometallics. Let’s take a look at the latest research on this compound (cas:503538-69-0).

Transition-metal-catalyzed asym. hydroalkenylation of alkenes provides an atom-economical method to build mol. complexity from easily available materials. Herein we report an iridium-catalyzed asym. hydroalkenylation of unconjugated alkenes with acrylamides and acrylates. The catalytic hydroalkenylation of norbornene derivatives occurred to form products with allylic stereocenters with high chemo-, regio-, and stereoselectivities. DFT calculations revealed that the migratory insertion is irreversible and the enantiodetn. step.

Different reactions of this compound((R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole)Product Details of 503538-69-0 require different conditions, so the reaction conditions are very important.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Wang, Cong-Shuai; Wei, Liang; Fu, Cong; Wang, Xin-Heng; Wang, Chun-Jiang published the article 《Asymmetric Synthesis of Axially Chiral Naphthyl-C3-indoles via a Palladium-Catalyzed Cacchi Reaction》. Keywords: axially chiral naphthyl indole preparation enantioselective; alkynylaniline naphthyl halide Cacchi reaction Pd chiral segphos catalyst.They researched the compound: (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole( cas:503538-69-0 ).Formula: C38H24F4O4P2. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:503538-69-0) here.

Atropoisomeric biaryl motifs are widely found in natural products and bioactive compounds as well as chiral catalysts and ligands. Various efficient approaches have been disclosed for the construction of chiral six-six biaryl skeletons. In contrast, the enantioselective synthesis of axially chiral arylindoles through the strategy of de novo construction, other than the asym. functionalization of indoles, remain a challenging task. Herein authors report an efficient Pd(0)/(S)-Segphos-catalyzed atroposelective Cacchi reaction of 2-alkynylanilines with sterically congested naphthyl halides, which afforded an array of naphthyl-C3-indoles in high yields with good to excellent atroposelectivities. The addition of water and the modulation of the manipulation procedure by premixing the palladium complex and the naphthyl halide were the keys to success. The conformational stability of the obtained axially chiral naphthyl-C3-indole containing a synthetically more-valuable free NH moiety is revealed through kinetic experiments

Different reactions of this compound((R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole)Formula: C38H24F4O4P2 require different conditions, so the reaction conditions are very important.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Synthetic Route of C12H10BrNO2. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: Ethyl 6-bromoquinoline-3-carboxylate, is researched, Molecular C12H10BrNO2, CAS is 481054-89-1, about Synthesis of 2,4-unsubstituted quinoline-3-carboxylic acid ethyl esters from arylmethyl azides via a domino process. Author is Tummatorn, Jumreang; Thongsornkleeb, Charnsak; Ruchirawat, Somsak; Gettongsong, Tanita.

A convenient synthesis of 2,4-unsubstituted quinoline-3-carboxylic acid Et esters via a domino process is described. The synthesis employs arylmethyl azides as the precursor which undergoes an acid-promoted rearrangement to give an N-aryl iminium ion. Following the addition with Et 3-ethoxyacrylate, intramol. electrophilic aromatic substitution, elimination and subsequent oxidation, the quinoline products were obtained in moderate to excellent yields.

Different reactions of this compound(Ethyl 6-bromoquinoline-3-carboxylate)Synthetic Route of C12H10BrNO2 require different conditions, so the reaction conditions are very important.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 6797-13-3, is researched, Molecular C9H9NO, about Trithiocyclopropenium ion as a building block for nitrogen heterocycle synthesis, the main research direction is thiocyclopropenium perchlorate synthon nitrogen heterocycle; cyclopropenium trithio perchlorate synthon nitrogen heterocycle.Application In Synthesis of 2-Ethylbenzo[d]oxazole.

A new methodol. for heterocycle synthesis using trithiocyclopropenium salt as a building block is described. Tris(tert-butylthio)cyclopropenium perchlorate (I) reacts with β-amino acids under basic conditions to give 1,2-dihydropyridines, where cyclopropenium salt serves as the 3 C homologator in heterocyclic ring formation. The selective syntheses of 1,5-benzodiazepines and benzimidazoles from I are also described. Reaction of I with o-phenylenediamines in DME gives 1,5-benzodiazepines as a single product but in MeOH benzimidazoles. The selective formation of 1,5-benzodiazepines and benzimidazoles could be accounted for by the solvent participation in the cyclization step.

Different reactions of this compound(2-Ethylbenzo[d]oxazole)Application In Synthesis of 2-Ethylbenzo[d]oxazole require different conditions, so the reaction conditions are very important.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 2-Mercapto-5-methylbenzimidazole, is researched, Molecular C8H8N2S, CAS is 27231-36-3, about Reaction of 3-iodo-4H-1-benzopyran-4-one with 2-mercaptobenzimidazoles, the main research direction is iodobenzopyranone condensation mercaptobenzimidazole; iodochromone condensation mercaptobenzimidazole.COA of Formula: C8H8N2S.

Refluxing 3-iodo-4H-1-benzopyran-4-one with 2-mercaptobenzimodazole in DMF in the presence of Bu4NCl for 2 h gave 68% 3-(2-benzimidazolylthio)-4H-1-benzopyran-4-one. Also prepared were 3-(5-methyl-2-benzimidazolylthio)-4H-1-benzopyran-4-one and 3-(2-imidazolylthio)-4H-1-benzopyran-4-one.

Different reactions of this compound(2-Mercapto-5-methylbenzimidazole)COA of Formula: C8H8N2S require different conditions, so the reaction conditions are very important.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Li, Zhenhua; Jin, Guoqiang; Qin, Jingjing; Tan, Zhiyong; He, Jiayu researched the compound: 2-Ethylbenzo[d]oxazole( cas:6797-13-3 ).SDS of cas: 6797-13-3.They published the article 《Efficient and divergent synthesis of benzoxazoles and 1,2-benzisoxazoles from o-hydroxyaryl ketoximes》 about this compound( cas:6797-13-3 ) in Heterocycles. Keywords: hydroxy acetophenone oxime tandem Beckmann rearrangement regioselective oxacyclization; benzoxazole preparation; benzisoxazole preparation. We’ll tell you more about this compound (cas:6797-13-3).

A bis(trichloromethyl) carbonate (BTC) / triphenylphosphine oxide (TPPO) system promoting tunable cyclization of a variety of o-hydroxyaryl ketoximes to benzoxazoles and benzisoxazoles was developed. The synthetic switch was enabled by base-free or the use of Et3N. Under base-free conditions, o-hydroxyaryl ketoximes were treated with BTC/TPPO giving corresponding 2-substituted benzoxazoles via cascaded Beckmann rearrangement and intramol. oxa-cyclization. Analogously, the 3-substituted benzisoxazoles were obtained via intramol. nucleophilic substitution reactions in the presence of Et3N. This process features mild reaction conditions, high chemoselectivity and good functional groups tolerance.

Different reactions of this compound(2-Ethylbenzo[d]oxazole)SDS of cas: 6797-13-3 require different conditions, so the reaction conditions are very important.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 503538-69-0, is researched, Molecular C38H24F4O4P2, about Enantioselective Ag-catalyzed allylation of aldimines, the main research direction is homoallylic amine enantioselective preparation; aldimine crotyl allyl trimethoxysilane enantioselective crotylation allylation; crotylation allylation silver catalyst chiral ligand.Name: (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole.

A highly enantioselective synthesis of homoallylic amines, using allyltrimethoxysilane under AgI catalytic conditions, has been developed. Among the chiral ligands investigated, a remarkable difference in the resulting AgI complexes was observed Under mild conditions and low catalyst loadings, homoallylamines were produced in high ee values (up to 80%) and good yields. The methodol. can be further extended to a diastereoselective and enantioselective crotylation of aldimines. © Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009.

Different reactions of this compound((R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole)Name: (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole require different conditions, so the reaction conditions are very important.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Electric Literature of C8H8N2S. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 2-Mercapto-5-methylbenzimidazole, is researched, Molecular C8H8N2S, CAS is 27231-36-3, about Synthesis of benzimidazo[2,1-b]benzothiazole derivatives through sequential Cu-catalyzed domino coupling and Pd-catalyzed Suzuki reaction. Author is Gao, Jilong; Zhu, Jiaoyan; Chen, Lubin; Shao, Yingying; Zhu, Jiaqi; Huang, Yijia; Wang, Xiaoxia; Lv, Xin.

A variety of benzo[d]benzo[4,5]imidazo[2,1-b]thiazoles were efficiently and conveniently synthesized from the Cu-catalyzed domino coupling of ortho-dihalo arenes with 2-mercaptobenzimidazoles. The reaction is also applicable to a series of multifunctional substrates, affording the halo-containing products with excellent selectivity. The brominated products can further react with arylboronic acids under Pd catalysis to furnish the arylated benzimidazo[2,1-b]benzothiazole derivatives

Different reactions of this compound(2-Mercapto-5-methylbenzimidazole)Electric Literature of C8H8N2S require different conditions, so the reaction conditions are very important.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Potowski, Marco; Antonchick, Andrey P.; Waldmann, Herbert published an article about the compound: (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole( cas:503538-69-0,SMILESS:FC1(F)OC2=CC=C(P(C3=CC=CC=C3)C4=CC=CC=C4)C(C5=C6OC(F)(F)OC6=CC=C5P(C7=CC=CC=C7)C8=CC=CC=C8)=C2O1 ).Synthetic Route of C38H24F4O4P2. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:503538-69-0) through the article.

A novel exo-selective [6+3] cycloaddition approach for the highly enantioselective synthesis of polysubstituted piperidines was developed. The developed methodol. was applied in a one-pot [6+3]-[4+2] dicycloaddn., allowing the construction of structurally and stereochem. rich polycyclic compounds from simple building blocks.

《Catalytic asymmetric exo-selective [6+3] cycloaddition of iminoesters with fulvenes》 provides a strategy for the preparation of materials with excellent comprehensive properties, which is conducive to broaden the application field of this compound((R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole)Synthetic Route of C38H24F4O4P2.

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem

Computed Properties of C9H9NO. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: 2-Ethylbenzo[d]oxazole, is researched, Molecular C9H9NO, CAS is 6797-13-3, about Building Heterocyclic Systems with RC(OR)2+ Carbocations in Recyclable Bronsted Acidic Ionic Liquids: Facile Synthesis of 1-Substituted 1H-1,2,3,4-Tetrazoles, Benzazoles and Other Ring Systems with CH(OEt)3 and EtC(OEt)3 in [EtNH3][NO3] and [PMIM(SO3H)][OTf]. Author is Aridoss, Gopalakrishnan; Laali, Kenneth K..

1-Aryl/alkyl-1H-1,2,3,4-tetrazoles can conveniently be synthesized in one-pot reactions from the corresponding amines by reaction with TMSN3 and CH(OEt)3 using the readily available, recyclable, Bronsted acidic ionic liquids [EtNH3][NO3] (IL-1) and [PMIM(SO3H)][OTf] [IL-2, 1-methyl-3-(propyl-3-sulfonyl)imidazolium trifluoromethanesulfonate] under mild conditions in high yields. Based on comparative reactions, whereas both ILs are excellent promoters, reactions are completed with shorter reaction times and in higher yields with IL-2. Among 24 examples provided, identical products were obtained via the two ILs, except in the case of 2-aminobenzoic acid where tetrazole was formed with IL-2 and 2-ethylquinazolin-4(3H)-one was formed with IL-1. By leaving out TMSN3 from the reaction, the in-situ formed CH(OEt)2+ and EtC(OEt)2+ (via their corresponding orthoesters) react under sonication with o-phenylenediamine bearing various substituents, o-aminothiophenol, and o-aminophenol to form a wide array of benzazoles (benzimidazole, benzothiazole, and benzoxazole) and quinazolin-4(3H)-one in high yields (18 examples). The two ILs reacted differently in reaction with 2-aminobenzamide, whereas quinazolin-4(3H)-one was formed with IL-2/CH(OEt)3, the “”unexpected”” N-ethylquinazolin-4(3H)-one was isolated with IL-1/CH(OEt)3. The latter was also formed from 2-aminobenzoic acid in IL-1/CH(OEt)3. Mechanistic implications are addressed. The reported protocols enable rapid assembly of a host of heterocyclic systems in high yields with the added advantage of recycling and re-use of the ILs.

The article 《Building Heterocyclic Systems with RC(OR)2+ Carbocations in Recyclable Bronsted Acidic Ionic Liquids: Facile Synthesis of 1-Substituted 1H-1,2,3,4-Tetrazoles, Benzazoles and Other Ring Systems with CH(OEt)3 and EtC(OEt)3 in [EtNH3][NO3] and [PMIM(SO3H)][OTf]》 also mentions many details about this compound(6797-13-3)Computed Properties of C9H9NO, you can pay attention to it, because details determine success or failure

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem