The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 1-(Furan-2-yl)propan-1-one( cas:3194-15-8 ) is researched.Application In Synthesis of 1-(Furan-2-yl)propan-1-one.Heathcock, Clayton H.; Gulick, L. Gray; Dehlinger, Thomas published the article 《Reaction of furyllithium with carboxylic acids》 about this compound( cas:3194-15-8 ) in Journal of Heterocyclic Chemistry. Keywords: furan acylated; acylated furan. Let’s learn more about this compound (cas:3194-15-8).
α-Furyllithium (prepared via BuLi) is treated with acids RCO2H to give mixtures of 2-furyl ketones [2-(RCO-substituted)-furans] (I) and difurylcarbinols [bis(2-furyl)-(R-substituted)-carbinols] (II). The I-II ratio is >1; N.M.R. spectral data for II are given.
After consulting a lot of data, we found that this compound(3194-15-8)Application In Synthesis of 1-(Furan-2-yl)propan-1-one can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem