151230-42-1, In an article, published in an article,authors is Chaadaj, Wojciech, once mentioned the application of 151230-42-1, Name is 6-Bromo-2-methylbenzo[d]oxazole,molecular formula is C8H6BrNO, is a conventional compound. this article was the specific content is as follows.
Mild and Functional Group Tolerant Method for Tandem Palladium-Catalyzed Carbocyclization-Coupling of ?-Acetylenic beta-Ketoesters with Aryl Bromides and Chlorides
We report a new protocol for the annulative difunctionalization of acetylenes via tandem carbocyclization-coupling of ?-acetylenic beta-ketoesters with aryl and heteroaryl bromides and chlorides catalyzed by the palladium species derived from an air- and moisture-stable palladacyclic precatalyst. In the tandem process, the palladium complex combines appropriate carbophilic Lewis acidity and redox activity to catalyze two mechanistically distinct reactions – nucleophilic addition of the enolate to unactivated alkyne, followed by C-C coupling. We found that a broad range of electronically varied aryl and heteroaryl bromides and chlorides underwent this reaction with various ?-acetylenic beta-ketoesters, providing corresponding substituted vinylidenecyclopentanes in high yield with excellent functional group tolerance.
151230-42-1, If you are hungry for even more, make sure to check my other article about 151230-42-1
Reference£º
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem