In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Computed Properties of C7H3Cl2NO, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 3621-81-6, name is 2,5-Dichlorobenzooxazole. In an article£¬Which mentioned a new discovery about 3621-81-6
The first large-scale synthesis of MK-4305: A dual orexin receptor antagonist for the treatment of sleep disorder
A new synthetic route to drug candidate 1, a potent and selective dual orexin antagonist for the treatment of sleep disorders, has been developed. The key acyclic precursor 10 was prepared in a one-step process in 75% isolated yield from commercially available starting materials using novel chemistry to synthesize 2-substituted benzoxazoles. A reductive amination was followed by a classical resolution to afford chiral diazepane (R)-11. Finally, coupling of (R)-11 with acid 5 furnished the desired drug candidate 1.
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Reference£º
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem