Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 22876-22-8, Name is 5-Methylbenzo[d]oxazole-2(3H)-thione, molecular formula is C8H7NOS, 22876-22-8, In a Article, authors is Ocura, Haruo£¬once mentioned of 22876-22-8
STUDIES ON HETEROCYCLIC COMPOUNDS. XXXIV. SYNTHESIS OF 2-SUBSTITUTED AMINOBENZOXAZOLES WITH NICKEL PEROXIDE
Oxidation of N-methyl (or phenyl)-N’-(4-methylpyrid-2-yl)thiourea (Ia, b) with nickel peroxide (Ni-PO) under reflux in benzene or acetonitrile afforded the corresponding ureas (IIa, b).N-(2-Hydroxy-5-methylphenyl)-N’-methylthiourea (IVa) was synthesized by the reaction of 2-amino-4-methylphenol (III) and methyl isothiocyanate in benzene under reflux.Howevwer, the reaction of III and phenyl isothiocyanate in benzene under reflux did not afford the thiourea (IVb) but IVb was obtained in ethanol at room temperature.NiPO oxidation of thioureas (IVa-f) in acetonitrile at room temperature afforded 2-substituted aminobenzoxazoles (VIIa-f) in good yields.The reaction mechanisms of Ni-PO and thioureas (Ia, b and IVa-f) are discussed.Keywords: – N-substituted N’-(4-methylpyrid-2-yl)thioureas; N-substituted N’-(4-methylpyrid-2-yl)ureas; N-(2-hydroxyphenyl) N’-substituted thioureas; 2-substituted aminobenzoxazoles; nickel peroxide; oxidative cyclization; 2-mercaptobenzoxazole; isothiocyanates
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.22876-22-8. In my other articles, you can also check out more blogs about 22876-22-8
Reference£º
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem