With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.73101-74-3,2-(Bromomethyl)benzo[d]oxazole,as a common compound, the synthetic route is as follows.,73101-74-3
General procedure: Pyridine derivative (0.2 mmol) was dissolved in dichloromethane(2 mL) and benzyl bromide derivative (1.2e2.0 equiv) wasthen added and the solutionwas heated to 50 C for 12 h in a sealedtube. After cooling at room temperature and concentration underreduced pressure, the resulting solid was triturated in diethyl ether,filtered and rinsed with diethyl ether to afford the compounds13e21, 33 and 41.
The synthetic route of 73101-74-3 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Azzouz, Rabah; Peauger, Ludovic; Gembus, Vincent; ?in?a?, Mihaela-Liliana; Papamicael, Cyril; Levacher, Vincent; Sopkova-de Oliveira Santos, Jana; European Journal of Medicinal Chemistry; vol. 145; (2018); p. 165 – 190;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem