Extracurricular laboratory: Synthetic route of 27231-36-3

The article 《Polarographic study of an alkyl benzimidazolyl sulfoxide and the corresponding sulfide and sulfone》 also mentions many details about this compound(27231-36-3)Synthetic Route of C8H8N2S, you can pay attention to it, because details determine success or failure

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Analytica Chimica Acta called Polarographic study of an alkyl benzimidazolyl sulfoxide and the corresponding sulfide and sulfone, Author is Johansson, Bo Lennart; Persson, Bjorn, which mentions a compound: 27231-36-3, SMILESS is SC1=NC2=CC(C)=CC=C2N1, Molecular C8H8N2S, Synthetic Route of C8H8N2S.

2-(5-Methylbenzimidazolyl)-1-(2-pyridyl)ethyl sulfide (I), II [69417-07-8], and III [69417-08-9] were reduced at a dropping Hg electrode in aqueous EtOH. Coulometric experiments at a Hg pool prove that 2-ethylpyridine [100-71-0] and 2-mercapto-5-methylbenzimidazole [27231-36-3] were formed in the reduction process of the sulfide and the sulfoxide. Coulometric reduction of the sulfone results in some conversion of the pyridine 1-oxide group together with a reductive fission of the ethyl-sulfonyl bond. One of these fission products undergoes secondary reactions. The concentration of 2-benzimidazolyl 2-pyridylmethyl sulfoxide (IV) [57237-97-5] in a pharmaceutical formulation was determined by differential pulse polarog.

The article 《Polarographic study of an alkyl benzimidazolyl sulfoxide and the corresponding sulfide and sulfone》 also mentions many details about this compound(27231-36-3)Synthetic Route of C8H8N2S, you can pay attention to it, because details determine success or failure

Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem