Extracurricular laboratory: Synthetic route of 59-49-4

As the rapid development of chemical substances, we look forward to future research findings about 59-49-4

2-Benzoxazolinone, cas is 59-49-4, it is a common heterocyclic compound, the benzoxazole compound, its synthesis route is as follows.,59-49-4

135.1 kg of 99.3% pure 2-benzoxazolone (VI) obtained by the procedure of Example 1 was mixed with 533.3 kg of liquid base (15%), stirred, and heated to 95-105 C,The pressure is from 0 to 0.15 MPa until the reaction is complete, and the hydrochloric acid is acidified to a pH of 7,Solid-liquid separation, 100.7 kg of o-aminophenol (VII) with a purity of 99.0%,The yield was 96.5%; the residual in the filtrate was extracted by extraction with dichloroethane.

As the rapid development of chemical substances, we look forward to future research findings about 59-49-4

Reference£º
Patent; Shao Yutian; (12 pag.)CN110156712; (2019); A;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem