Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 6674-22-2, Name is 2,3,4,6,7,8,9,10-Octahydropyrimido[1,2-a]azepine, molecular formula is , belongs to benzoxazole compound. In a document, author is Wang, Junfeng, COA of Formula: C9H16N2.
Efficient synthesis of NIR emitting bis [2-(2 ‘-hydroxylphenyl)benzoxazole] derivative and its potential for imaging applications
Unassymetric bis[2-(2’-hydroxyphenylbenzoxole)] bis(HBO) derivatives with a DPA functionality for zinc binding have been developed with an efficient synthetic route, using the retrosynthetic analysis. Comparison of bis(HBO) derivatives with different substitution patterns allows us to verify and optimize their unique fluorescence properties. Upon binding zinc cation, bis(HBO) derivatives give a large fluorescence turn-on in both visible (lambda(em) approximate to 536 nm) and near-infrared (NIR) window (lambda(em) approximate to 746 nm). The probes are readily excitable by a 488 nm laser, making this series of compounds a suitable imaging tool for in vitro and in vivo study on a confocal microscope. The application of zinc binding-induced fluorescence turn-on is successfully demonstrated in cellular environments and thrombus imaging.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 6674-22-2, in my other articles. COA of Formula: C9H16N2.
Reference:
Benzoxazole – Wikipedia,
,Benzoxazole | C7H5NO – PubChem