New Advances in Chemical Research in 2021.The dynamic chemical diversity of the numerous elements, ions and molecules that constitute the basis of life provides wide challenges and opportunities for research. 590-67-0, Name is 1-Methylcyclohexanol, molecular formula is , belongs to benzoxazole compound. In a document, author is Jilani, Jamal Abdellatif, Application of 590-67-0.
The synthesis of a series of 2-arylbenzoxazole compounds possessing a cytotoxic activity as potential anticancer agents was achieved. Oxidative coupling of benzaldehyde with o-aminophenol utilizing lead tetraacelate approach was used to realize the synthesis of compounds 1-11. The cytotoxicity of 1-11 was screened against breast cancer cell line MCF-7 and human colon cancer cell line HCT-116 utilizing doxorubicin as a reference drug. Among these compounds, 2-(3-benzyloxyphenyl)benzoxazole-5-acetic acid (5) and 2-(4-methoxyphenyl)benzoxazol-5-acetic acid (10), were found to be promising cytotoxic compounds against the MCF-7 cell line. In addition, this study showed that the presence of an acetic acid group at position 5 of the benzoxazole nucleus enhances the activity. Moreover, we noticed that the presence of an oxygen atom directly linked to the phenyl substituent improves activity as well. These results offer a new benzoxazole based template to design and develop novel antineoplastic agents.
Application of 590-67-0, Consequently, the presence of a catalyst will permit a system to reach equilibrium more quickly, but it has no effect on the position of the equilibrium as reflected in the value of its equilibrium constant.I hope my blog about 590-67-0 is helpful to your research.
Reference:
Benzoxazole – Wikipedia,
,Benzoxazole | C7H5NO – PubChem