1750-45-4, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 5-Chloro-6-hydroxybenzo[d]oxazol-2(3H)-one, cas is 1750-45-4,the benzoxazole compound, it is a common compound, a new synthetic route is introduced below.
5-chloro-6-hydroxy-1,3-benzoxazol-2(3H)-one (0.93 g, 5 mmol) and imidazole (1.00 g, 15 mmol) were dissolved in dimethylformamide (10 mL) with stirring under inert atmosphere. Triisopropylsilylchloride (1.15 g, 6 mmol) was added and the resulting solution was stirred for 3 days. The reaction mixture was partitioned between water and heptane. The organic layer was washed with water and dried over magnesium sulphate, filtrated and concentrated, to give 1.45 g (85%) of the subtitled compound as a grey solid. APCI-MS: m/z 342 [MH+]
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 1750-45-4, 5-Chloro-6-hydroxybenzo[d]oxazol-2(3H)-one
Reference：
Patent; ASTRAZENECA AB; WO2004/5295; (2004); A1;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem