The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole( cas:503538-69-0 ) is researched.Quality Control of (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole.Zieba, Andrzej; Hooper, Joel F. published the article 《Palladium-Catalysed Carboborylation for the Synthesis of Borylated Indanes》 about this compound( cas:503538-69-0 ) in European Journal of Organic Chemistry. Keywords: palladium catalyst carboborylation stereoselective cyclization borylation alkene; borylated indane preparation chiral substituent effect. Let’s learn more about this compound (cas:503538-69-0).
A palladium-catalyzed carboborylation reaction for the synthesis of borylated indanes has been investigated. This reaction proceeds in good yields with an achiral catalyst, and is tolerant of substitution on the aryl ring, although sensitivity to the substitution of the alkene was observed Initial studies towards an enantioselective version of this reaction were undertaken, identifying phosphoramidites as a promising ligand class. This allowed for the synthesis of chiral indane and indolone products with moderate levels of enantioselectivity.
Compounds in my other articles are similar to this one((R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole)Quality Control of (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.
Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem