90322-32-0, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 2-Methylbenzo[d]oxazole-5-carboxylic acid, cas is 90322-32-0,the benzoxazole compound, it is a common compound, a new synthetic route is introduced below.
Step 2 – Preparation of Intermediate E 5-Carboxy-2-methylbenzoxazole (8.9 g) and methyl- p -toluenesulfonate (11.16 g) were combined and heated to 200C with stirring for 10 minutes. The mixture became a brown liquid and mild boiling occured. The reaction was cooled to room temperature and the liquid solidified. Acetone (50 ml) was added, and with constant heating at reflux, the product was broken up with a spatula. The resulting slurry was heated at reflux for 15 minutes with rapid stirring and the off-white product was collected by filtration. This product was slurried again in refluxing acetone for 30 minutes, filtered, washed with ligroin P950, and dried to yield 9.3 g of 5-carboxy-2,3-dimethylbenzoxazolium p -toluene-sulfonate (Intermediate D).
The chemical industry reduces the impact on the environment during synthesis,90322-32-0,2-Methylbenzo[d]oxazole-5-carboxylic acid,I believe this compound will play a more active role in future production and life.
Reference：
Patent; EASTMAN KODAK COMPANY, (a New Jersey corporation); EP323728; (1989); A2;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem