Synthesis and reactions of 3,4-dihydro-2H-1,4-benzoxazine derivatives was written by Kotha, Sambasivarao;Bindra, Vandana;Kuki, Atsuo. And the article was included in Heterocycles in 1994.Electric Literature of C9H9NO This article mentions the following:
Several 3,4-dihydro-2H-1,4-benzoxazine derivatives, e.g., I (R = H, Me), were prepared from com. available benzoxazoles II by use of an efficient two step sequence. Thus, II were reduced to give ring opened aminophenols which were cyclized with BrCH2CH2Br to give I. Aryl functionalization reactions allowing access to further benzoxazine derivatives are also described. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Electric Literature of C9H9NO).
2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazole derivatives have different biological activities. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as anti-inflammatory, antimycobacterial, antihistamine.Electric Literature of C9H9NO
Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem