Chlorination and ortho-acetoxylation of 2-arylbenzoxazoles was written by Leng, Yuting;Yang, Fan;Zhu, Weiguo;Wu, Yangjie;Li, Xiang. And the article was included in Organic & Biomolecular Chemistry in 2011.Product Details of 99586-31-9 This article mentions the following:
Efficient and facile catalytic protocols for chlorination and ligand-directed ortho-acetoxylation of 2-arylbenzoxazoles have been developed. The chlorination is not a ligand-directed ortho-functionalization, but an electrophilic substitution process in the benzo ring of the benzoxazole moiety. Meanwhile, the acetoxylation exhibited high regioselectivity for the substrates containing a meta-substituent and occurred at the less sterically hindered ortho-C-H bond of the directing group. In the experiment, the researchers used many compounds, for example, 2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9Product Details of 99586-31-9).
2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9) belongs to benzoxazole derivatives. The benzoxazole moiety is widely found in various natural compounds, which are often found to be biologically active. In the past years, numerous benzoxazole derivatives have been synthesised and evaluated for their biological potential.Product Details of 99586-31-9
Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem