Microwave-assisted efficient one-step synthesis of amides from ketones and benzoxazoles from (2-hydroxyaryl) ketones with acetohydroxamic acid using sulfuric acid as the catalyst was written by Madabhushi, Sridhar;Chinthala, Narsaiah;Vangipuram, Venkata Sairam;Godala, Kondal Reddy;Jillella, Raveendra;Mallu, Kishore Kumar Reddy;Beeram, China Ramanaiah. And the article was included in Tetrahedron Letters in 2011.SDS of cas: 5676-58-4 This article mentions the following:
An efficient 1-step method for the synthesis of amides and benzoxazoles directly from ketones and 2-hydroxyaryl ketones, resp., by the reaction with AcNHOH using H2SO4 as catalyst was described. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4SDS of cas: 5676-58-4).
2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. The benzoxazole moiety is widely found in various natural compounds, which are often found to be biologically active. The wide range in therapeutic potential of benzoxazole derivatives is related to the favourable interactions of the benzoxazole moiety with different protein targets.SDS of cas: 5676-58-4
Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem