1. The impurity of diuretic hydrochlorothiazide 04, also be a medical intermediate.
2. It’s mainly used for the detection of drug impurities, the synthesis of hydrochlorothiazide and the screening of medical structural fragments.
3. Presents a weak alkaline,refrigeration.
. Recommended Products is: 5250-72-6 and 22503-72-6.
Dichloro-isoproterenol (I) is known to prevent both adrenaline (II)-induced increase of contractile force and activation of phosphorylase in the dog heart in situ. The present study demonstrates that I almost completely abolishes the increase in blood sugar and free fatty acids induced by II, noradrenaline (III), and isoproterenol in the dog. The hyperlactic-acidemic effect of II is partly blocked. I does not block II-induced hyperglycemia in mice. In contrast to I, phenoxybenzamine (IV) does not affect the hyperglycemia or increase in blood lactic acid induced by II in the dog. Ergotamine antagonizes the hyperglycemia but not the increase in lactic acid. IV effectively blocks the vasopressor response to II and III, and ergotamine produces maximal reversal of II. None of these drugs in the doses used antagonized the pos. inotropic effect of adrenergic stimuli. Both I and IV increase blood glucose and lactic acid. High doses of I appear to antagonize the hyperglycemic action of low doses. The hyperglycemia and lactic acid increase produced by IV are antagonized by I. I also produces a marked and sustained increase in free fatty acids even with doses which do not block the action of II. Possible mechanisms of action are discussed.
Effect of adrenergic blocking agents on some metabolic actions of catechol amines. Recommended basis is hydrochlorothiazide 20. Products is: https://www.ambeed.com/products/742-20-1.html, 432499-63-3
Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem