Synthesis of Benzoxazoles from 2-Aminophenols and β-Diketones Using a Combined Catalyst of Bronsted Acid and Copper Iodide was written by Mayo, Muhammad Shareef;Yu, Xiaoqiang;Zhou, Xiaoyu;Feng, Xiujuan;Yamamoto, Yoshinori;Bao, Ming. And the article was included in Journal of Organic Chemistry in 2014.COA of Formula: C9H9NO This article mentions the following:
Cyclization reactions of 2-aminophenols with β-diketones catalyzed by a combination of Bronsted acid and CuI are presented. Various 2-substituted benzoxazoles were obtained through these reactions. Different substituents such as Me, chloro, bromo, nitro, and methoxy on 2-aminophenol are tolerated under the optimized reaction conditions. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4COA of Formula: C9H9NO).
2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazole derivatives have different biological activities. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as antibacterial, antifungal, anticancer.COA of Formula: C9H9NO
Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem