On March 5, 2020, Mete, Antonio; Hitchin, James R.; Graham, Mark published a patent.Safety of Methyl benzo[d]oxazole-7-carboxylate The title of the patent was Heterocyclic compounds as ARH modulators for treatment of diseases, in particular cancer. And the patent contained the following:
The present invention relates compounds of the general formula (I) or (II) which are ARH inhibitors, methods for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds and pharmaceutical compositions for the treatment or prevention of diseases, in particular cancer or conditions with dysregulated immune functions, or other conditions associated with aberrant AHR signaling, as a sole agent of in combination with other active ingredients. Such compounds may also be of utility in the expansion of hematopoietic stem cells (HSCs) and the use of HSCs in autologous or allogenic transplantation for the treatment of patients with inherited immunol. and autoimmune diseases and diverse hematopoietic disorders. The experimental process involved the reaction of Methyl benzo[d]oxazole-7-carboxylate(cas: 1086378-35-9).Safety of Methyl benzo[d]oxazole-7-carboxylate
The Article related to heterocyclic arh modulator signaling cancer, Pharmaceuticals: Formulation and Compounding and other aspects.Safety of Methyl benzo[d]oxazole-7-carboxylate
Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem