Chemistry is an experimental science, Computed Properties of C9H22O3SSi, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 14814-09-6, Name is 3-Mercaptopropyltriethoxysilane, molecular formula is C9H22O3SSi, belongs to benzoxazole compound. In a document, author is Greenhalgh, Mark D..
Multiple roles of aryloxide leaving groups in enantioselective annulations employing alpha,beta-unsaturated acyl ammonium catalysis
An isothiourea-catalysed Michael addition-annulation process using -fluoroalkyl-substituted ,-unsaturated aryl esters and a range of 2-acylbenzazoles is reported for the enantioselective synthesis of dihydropyranone and dihydropyridinone products bearing polyfluorinated stereocenters (29 examples, up to 98% yield, >99:1 er). The choice of aryl group of the aryl ester proved essential in determining reaction enantioselectivity and dihydropyranone:dihydropyridinone product selectivity. The aryloxide leaving group is shown to play a number of essential additional roles, operating (i) as a BrOnsted base, circumventing the need for an auxiliary base; and (ii) as a Lewis base to catalyse the isomerisation of dihydropyranone products into thermodynamically-favoured dihydropyridinones. After optimisation, this isomerisation process was exploited for the selective synthesis of dihydropyridinone products using acylbenzothiazoles, and either dihydropyranone or dihydropyridinone products using acylbenzoxazoles. Finally, the phenol derivative, produced following protonation of the aryloxide, is proposed to act as a BrOnsted acid, which promotes an isothiourea-catalysed kinetic resolution of benzoxazole-derived dihydropyranones.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 14814-09-6. Computed Properties of C9H22O3SSi.
Reference:
Benzoxazole – Wikipedia,
,Benzoxazole | C7H5NO – PubChem