New discoveries in chemical research and development in 2021. As an important bridge between the micro, chemistry is one of the main methods and means for humans to understand and transform the material world. In an article, author is Gharpure, Santosh J., once mentioned the application of 352-34-1, HPLC of Formula: https://www.ambeed.com/products/352-34-1.html, category is benzoxazole. Now introduce a scientific discovery about this category.
Synthesis and isolation of highly unstable azirinobenzoxazole and benzoxazines in a chemodivergent fashion from aryl azido vinylogous carbonates by simple change in transition metal acetate is described. Thermal or rhodium(II) acetate-mediated decomposition of these azides gave dihydroazirino benzoxazole. Their nickel(II) acetate-promoted reaction gave 4-dihydro-2H-benzoxazines, whereas copper(II) acetate led to the corresponding oxidized imine derivatives. Benzaoxazine derivative could be kinetically resolved using a proline-catalyzed Mannich reaction. The benzoxazines were rapidly elaborated to angularly fused tetracyclic systems and coumarin-fused derivatives in a one pot fashion.
But sometimes, even after several years of basic chemistry education, it is not easy to form a clear picture on how they govern reactivity! 352-34-1, you can contact me at any time and look forward to more communication. HPLC of Formula: https://www.ambeed.com/products/352-34-1.html.
Reference:
Benzoxazole – Wikipedia,
,Benzoxazole | C7H5NO – PubChem