More research is needed about 6-Bromo-2-methylbenzo[d]oxazole

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, SDS of cas: 151230-42-1, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 151230-42-1

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, SDS of cas: 151230-42-1, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 151230-42-1, Name is 6-Bromo-2-methylbenzo[d]oxazole, molecular formula is C8H6BrNO

Discovery of 4-Piperazine Isoquinoline Derivatives as Potent and Brain-Permeable Tau Prion Inhibitors with CDK8 Activity

Tau prions feature in the brains of patients suffering from Alzheimer’s disease and other tauopathies. For the development of therapeutics that target the replication of tau prions, a high-content, fluorescence-based cell assay was developed. Using this high-content phenotypic screen for nascent tau prion formation, a 4-piperazine isoquinoline compound (1) was identified as a hit with an EC50 value of 390 nM and 0.04 Kp,uu. Analogs were synthesized using a hypothesis-based approach to improve potency and in vivo brain penetration resulting in compound 25 (EC50 = 15 nM; Kp,uu = 0.63). We investigated the mechanism of action of this series and found that a small set of active compounds were also CDK8 inhibitors.

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, SDS of cas: 151230-42-1, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 151230-42-1

Reference£º
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem