Chemistry is an experimental science, Computed Properties of https://www.ambeed.com/products/6825-20-3.html, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 6825-20-3, Name is 3,6-Dibromo-9H-carbazole, molecular formula is C12H7Br2N, belongs to benzoxazole compound. In a document, author is Zheng, Ling-Li.
Pd/Cu bimetallic co-catalyzed direct 2-arylation of benzoxazole with aryl chloride
An efficient Palladium/Copper bimetallic co-catalyzed direct 2-arylation of benzoxazoles with aryl chlorides is presented. The Pd(OAc)(2)/Cul/NiXantphos-based catalyst enables the installation of various aryl and heteroaryl groups in good to excellent yields (75-99%). Preliminary mechanism investigation indicates that Pd/Nixantphos complex activates C-Cl bond of aryl chlorides via oxidative addition, and Cu/Nixantphos complex chelates with nitrogen atom to lower the pK(a) of the 2-H in benzoxazoles. (C) 2019 Elsevier Ltd. All rights reserved.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 6825-20-3, in my other articles. Computed Properties of https://www.ambeed.com/products/6825-20-3.html.
Reference:
Benzoxazole – Wikipedia,
,Benzoxazole | C7H5NO – PubChem