Reference of 208772-23-0, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.208772-23-0, Name is Benzo[d]oxazole-4-carboxylic acid, molecular formula is C8H5NO3. In a article£¬once mentioned of 208772-23-0
Efficacious inhaled PDE4 inhibitors with low emetic potential and long duration of action for the treatment of COPD
Oral phosphodiesterase 4 (PDE4) inhibitors, such as cilomilast and roflumilast, have been shown to be efficacious against chronic obstructive pulmonary disease (COPD). However, these drugs have been hampered by mechanism-related side effects such as nausea and emesis at high doses. Compounds administered by inhalation are delivered directly to the site of action and may improve the therapeutic index required to overcome side effects. This paper describes systematic and rational lead optimization to deliver highly potent, long-acting, and efficacious preclinical inhaled PDE4 inhibitors with low emetic potential.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 208772-23-0
Reference£º
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem