19219-99-9, 5-Chloro-2-methylbenzo[d]oxazole is a benzoxazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
A mixture of commercially available 5-chloro-2-methylbenzo[d]oxazole(300 mg, 1.79 mmol), NBS (478 mg, 2.70 mmol) in carbon tetrachloride (6 mL) was heated under light for 4 hours. After cooling to room temperature, hexanes was added to the reaction mixture. The solids were filtered and the solvent was removed to give the crude product. Purification using 2 % ethyl acetate in hexane afforded the product (124 mg, 28 % yield). 1H NMR (CDCl3, 300 MHz) delta: 7.71 (s, 1H), 7.46 (d, J= 9.9 Hz, 1H), 7.36 (d, J= 8.7 Hz, 1H), 4.56 (s, 2H).
The synthetic route of 19219-99-9 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY; UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY; LAVOIE, Edmond J.; PARHI, Ajit; ZHANG, Yongzheng; PILCH, Daniel S.; KAUL, Malvika; WO2013/142712; (2013); A1;,
Benzoxazole – Wikipedia
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