3889-13-2, 5-Nitro-2,3-dihydro-1,3-benzoxazol-2-one is a benzoxazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Step 2. A mixture of 5-nitrobenzo[d]oxazol-2(3H)-one (3.60 g, 20.0 mmol), benzyl bromide (2.61 mL, 22.0 mmol) and cesium carbonate (7.81 g, 23.98 mmol) in DMF (50 mL) was sealed and heated in a microwave system at 85 C for 2 h. The reaction mixture was poured into water (500 mL), heated with a heat gun to near boiling and allowed to cool to rt with stirring. The resulting solids were collected by filtration, washed with water and hexanes and dried in vacuo to afford 3-benzyl-5-nitrobenzo[d]oxazol-2(3H)-one (5.20 g) as a gray solid. NMR (400 MHZ, DMSO-de) delta ppm 8.22 – 8.06 (m, 2H), 7.63 (d, J=8.8 Hz, 1H), 7.50 – 7.20 (m, 5H), 5.17 (s, 2H).
3889-13-2, The synthetic route of 3889-13-2 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; VIIV HEALTHCARE (No.5) LIMITED; BENDER, John A.; LOPEZ, Omar D.; NGUYEN, Van N.; YANG, Zhong; WANG, Alan Xiangdong; WANG, Gan; MEANWELL, Nicholas A.; BENO, Brett R.; FRIDELL, Robert A.; BELEMA, Makonen; THANGATHIRUPATHY, Srinivasan; (350 pag.)WO2016/172425; (2016); A1;,
Benzoxazole – Wikipedia
Benzoxazole | C7H5NO – PubChem