Electric Literature of C8H8N2S. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 2-Mercapto-5-methylbenzimidazole, is researched, Molecular C8H8N2S, CAS is 27231-36-3, about Synthesis of benzimidazo[2,1-b]benzothiazole derivatives through sequential Cu-catalyzed domino coupling and Pd-catalyzed Suzuki reaction. Author is Gao, Jilong; Zhu, Jiaoyan; Chen, Lubin; Shao, Yingying; Zhu, Jiaqi; Huang, Yijia; Wang, Xiaoxia; Lv, Xin.
A variety of benzo[d]benzo[4,5]imidazo[2,1-b]thiazoles were efficiently and conveniently synthesized from the Cu-catalyzed domino coupling of ortho-dihalo arenes with 2-mercaptobenzimidazoles. The reaction is also applicable to a series of multifunctional substrates, affording the halo-containing products with excellent selectivity. The brominated products can further react with arylboronic acids under Pd catalysis to furnish the arylated benzimidazo[2,1-b]benzothiazole derivatives
Different reactions of this compound(2-Mercapto-5-methylbenzimidazole)Electric Literature of C8H8N2S require different conditions, so the reaction conditions are very important.
Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem