TiO2-ZrO2 composite: Synthesis, characterization and application as a facile, expeditious and recyclable catalyst for the synthesis of 2-aryl substituted benzoxazole derivatives was written by Patil, Mahadeo R.;Bhanushali, Jayesh T.;Nagaraja, Bhari Mallanna;Keri, Rangappa S.. And the article was included in Comptes Rendus Chimie in 2018.HPLC of Formula: 99586-31-9 This article mentions the following:
The activity of an efficient mesoporous TiO2-ZrO2 composite catalyst for the synthesis of 2-aryl substituted benzoxazole derivatives using 2-aminophenol and substituted benzaldehydes/heterocyclic aldehydes at moderate temperature was studied. The catalyst was prepared by a co-precipitation method and characterized by X-ray diffraction, BET surface area and SEM. The effect of temperature, solvents and catalyst concentration on the synthesis of benzoxazole derivatives was systematically investigated. Short reaction times, green-reaction profiles, good to excellent yields, reliable cost efficiency, simple workup conditions and reusability of an eco-friendly catalyst were the noteworthy highlights of the reported method. The catalyst could be easily recovered and reused several times without any significant loss in the yield. The use of the present catalytic system to mediate the title chem. synthesis in a synthetic operation was important for the development of new atom-economic strategies and this was efficient in building complex structures from simple starting materials in an environmentally benign fashion. In the experiment, the researchers used many compounds, for example, 2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9HPLC of Formula: 99586-31-9).
2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9) belongs to benzoxazole derivatives. The benzoxazole moiety is widely found in various natural compounds, which are often found to be biologically active. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as antiparkinson, inhibition of hepatitis C virus, 5-HT3 antagonistic effect.HPLC of Formula: 99586-31-9
Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem