1. Trivial name: delta-Cadinene.
2. It’s mainly derived from flue-cured tobacco, burley tobacco and flavoured tobacco, it has a strong aroma and a good fixing effect, suitable for perfume, cosmetics, can also be used in wine, cigarettes, and toothpaste.
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This study analyzed the chem. composition and anti-osteoporosis activity of the n-hexane extract of Homalomena gigantea rhizome. Sixty compounds, representing 92.0% of the extract, were identified by gas chromatog.-mass spectrometry. Linalool (15.3%), oplopanone (9.8%), (¦¥)-¦Á-atlantone (5.6%), khusinol acetate (5.4%), bullatantriol (4.3%), and ¦Â-sitosterol (3.8%) were the main constituents. The anti-osteoporotic activity of the n-hexane extract was determined by measuring alk. phosphatase (ALP) activity, collagen content, and the mineralization of MC3T3-E1 cells. At concentrations of 4.0 and 20.0 ¦Ìg/mL, the n-hexane extract increased ALP activity by 8.2% and 23.7%, and increased collagen secretion by MC3T3-E1 cells by 114.9% and 112.4%, resp. At 4 ¦Ìg/mL, the extract significantly promoted the mineralization of MC3T3-E1 cells by as much as 133.2% compared to the neg. control. These results suggested that H. gigantea rhizome contains a natural anti-osteoporotic compound
Volatile Constituents and Anti-Osteoporotic Activity of the n-Hexane Extract From Homalomena gigantea Rhizome. Recommended basis is Cadinene. Products is: https://www.ambeed.com/products/189165-77-3.html, 51905-84-1
Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem