Properties and Exciting Facts About 2,5-Dichlorobenzooxazole

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Chemistry is traditionally divided into organic and inorganic chemistry. category: benzoxazole, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent£¬Which mentioned a new discovery about 3621-81-6

A process for preparing Suvorexant intermediate and its analogs of the method (by machine translation)

The invention discloses a method for preparing 8A shown Suvorexant intermediate and its analogs, or its pharmaceutically acceptable salt or solvate of the method, wherein R is hydrogen or C1 – C6 Alkyl, comprises the following steps: formula 3A protection of amino group in compound, formula 4A compound; d, in order to type 4A compound preparation formula 5A compound; e, in order to type 5A preparation formula 6A compound; f, formula 6A compound of formula 10A process for preparing the compound of the formula 7A compound; g, in order to type 7A compound preparation formula 8A compound. The method of the invention, by the novel process route of synthesis of compound 8, longer use this as the intermediate Suvorexant, effectively solves Suvorexant in the method of preparing the use of toxic substances, the cost is high, and the low yield of the the route is long, is suitable for industrial application. (by machine translation)

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Reference£º
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem