The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole( cas:503538-69-0 ) is researched.COA of Formula: C38H24F4O4P2.Aida, Yukimasa; Sugiyama, Haruki; Uekusa, Hidehiro; Shibata, Yu; Tanaka, Ken published the article 《Rhodium-Catalyzed Asymmetric [2 + 2 + 2] Cycloaddition of α,ω-Diynes with Unsymmetrical 1,2-Disubstituted Alkenes》 about this compound( cas:503538-69-0 ) in Organic Letters. Keywords: rhodium catalyzed asym cycloaddition diyne unsym alkene; axial chiral biaryl phosphine rhodium complex cycloaddition catalyst; multicyclic compound enantioselective preparation. Let’s learn more about this compound (cas:503538-69-0).
It has been established that a cationic rhodium(I)/axially chiral biaryl bisphosphine complex catalyzes the asym. [2 + 2 + 2] cycloaddition of α,ω-diynes with electron-rich and unstrained unsym. 1,2-disubstituted alkenes to give chiral multicyclic compounds with good yields and ee values. Interestingly, enantioselectivity highly depends on the structures of α,ω-diynes used presumably due to the presence of two distinct reaction pathways.
Here is a brief introduction to this compound(503538-69-0)COA of Formula: C38H24F4O4P2, if you want to know about other compounds related to this compound(503538-69-0), you can read my other articles.
Reference:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem