Safety of 4,4′-Dibromobiphenyl. I found the field of Chemistry very interesting. Saw the article Synthesis and Microbiological Properties of Novel Bis-Quaternary Ammonium Compounds Based on Biphenyl Spacer published in 2019, Reprint Addresses Vereshchagin, AN (corresponding author), Russian Acad Sci, ND Zelinsky Inst Organ Chem, 47 Leninsky Procpekt, Moscow 119991, Russia.. The CAS is 92-86-4. Through research, I have a further understanding and discovery of 4,4′-Dibromobiphenyl.
Novel gemini (tail-head-spacer-head-tail) bis-quaternary ammonium compounds (bis-QACs) with a biphenyl spacer between two pyridinium heads were synthesized and compared with commonly used antiseptics such as benzalkonium chloride (BAC) and chlorhexidine digluconate (CHG). The series of compounds showed high inhibitory activity against five bacterial strains and two fungi. The compounds, which contain C8H17-C10H21 aliphatic tails best within the series. A counterion change does not affect MIC in general. Cytotoxicity on human embryonic kidney cells and haemolysis were also investigated. For bis-QACs cytotoxic effect was lower than for 3,3 ‘-[1,4-phenylenebis(oxy)]bis(1-dodecylpyridinium) dibromide (3PHBO-12), that is their closest structural analogue, and for BAC.
Safety of 4,4′-Dibromobiphenyl. About 4,4′-Dibromobiphenyl, If you have any questions, you can contact Vereshchagin, AN; Gordeeva, AM; Frolov, NA; Proshin, PI; Hansford, KA; Egorov, MP or concate me.
Reference:
Benzoxazole – Wikipedia,
,Benzoxazole | C7H5NO – PubChem