Cobalt-catalyzed intramolecular C-N and C-O cross-coupling reactions: synthesis of benzimidazoles and benzoxazoles was written by Saha, Prasenjit;Ali, Ashif Md.;Ghosh, Pokhraj;Punniyamurthy, Tharmalingam. And the article was included in Organic & Biomolecular Chemistry in 2010.Recommanded Product: 2-(3-Bromophenyl)benzo[d]oxazole This article mentions the following:
Cobalt(II)-complex catalyzes efficiently the intramol. C-N and C-O cross-couplings of Z-N’-(2-halophenyl)-N-phenylamidines, e.g. I, and N-(2-bromophenyl)benzamides, e.g. II, to afford the corresponding substituted benzimidazoles and benzoxazoles, e.g. III [X = NPh, O], in the presence of K2CO3 at moderate temperature The protocol is general, air stable and affords the products selectively in moderate to high yield. In the experiment, the researchers used many compounds, for example, 2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9Recommanded Product: 2-(3-Bromophenyl)benzo[d]oxazole).
2-(3-Bromophenyl)benzo[d]oxazole (cas: 99586-31-9) belongs to benzoxazole derivatives. Being a heterocyclic compound, benzoxazole finds use in research as a starting material for the synthesis of larger, usually bioactive structures. The wide range in therapeutic potential of benzoxazole derivatives is related to the favourable interactions of the benzoxazole moiety with different protein targets.Recommanded Product: 2-(3-Bromophenyl)benzo[d]oxazole
Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem