Reactions of phosphorus compounds. 36. Heterocyclic synthesis via methylenetriphenylphosphorane extrusion was written by Schweizer, Edward E.;DeVoe, Susan V.. And the article was included in Journal of Organic Chemistry in 1975.Reference of 5676-58-4 This article mentions the following:
Addnl. data considered in abstracting and indexing are available from a source cited in the original document. A novel ylide elimination reaction gave 2-methylbenzothiazole (I), 2-methylquinazol-4-one (II), and 2,5-dimethylbenzoxazole (III) in greater than 62% yield. IV, V, and VI reacted with HCCCH2PPh3Br via the corresponding VII to give I, II, and III. The ylide formed from IV was not isolated. The reaction is a general heterocyclic synthesis. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Reference of 5676-58-4).
2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Benzoxazole nucleus is one of the most important heterocyclic compounds exhibiting remarkable pharmacological activities. Benzoxazoles are prominent in medicinal chemistry due to their wide spectrum of pharmacological activities such as antibacterial, antifungal, anticancer.Reference of 5676-58-4
Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem