Synthesis and polymorphism of 2-(4′-nitrostyryl)benzoxazole and its derivatives was written by Shen, Yongjia;Han, Pingyang;Ren, Shengwu. And the article was included in Huadong Huagong Xueyuan Xuebao in 1990.Product Details of 5676-58-4 This article mentions the following:
2-(4′-Nitrostyryl)-benzoxazole and its 5-Me, nitro, acetamino, and Ph derivatives were synthesized. Their thermal behaviors and polymorphism were determined by DSC and x-ray diffraction. They have α, β modifications; the α-modification is thermo-unstable and can transform into the β-modification on heating. The ΔHm, ΔSm, and m.p. of the α-modification are lower than those of the β-modification. The melt of the α-modification is a supercooled liquid in contrast to the β-modification. In the experiment, the researchers used many compounds, for example, 2,5-Dimethylbenzoxazole (cas: 5676-58-4Product Details of 5676-58-4).
2,5-Dimethylbenzoxazole (cas: 5676-58-4) belongs to benzoxazole derivatives. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization. A number of marketed drugs are available having benzoxazole as core active moiety like, nonsteroidal anti-inflammatory drug (NSAID)—flunoxaprofen, benoxaprofen, antibiotic—calcimycin.Product Details of 5676-58-4
Referemce:
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem