Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. COA of Formula: C9H7NO2. Introducing a new discovery about 122433-29-8, Name is 1-(Benzo[d]oxazol-2-yl)ethanone
Design, synthesis and in vitro evaluation on glucosamine-6P synthase of aromatic analogs of 2-aminohexitols-6P
The aminosugars are very important structural components of bacterial and fungi cell walls. Glucosamine-6-phosphate synthase (GlmS), which catalyses the first step of the aminosugar biosynthetic pathway i.e. the formation of D-glucosamine-6-phosphate from D-fructose-6- phosphate, is therefore an interesting target in the fight against microorganisms. In this work is described the synthesis of aromatic analogs of 2-amino-2-deoxy-D-glucitol-6- phosphate (ADGP) and its epimer 2-amino-2-deoxy-D-manitol-6-phosphate (ADMP), two important inhibitors of GlmS. The aromatic analogs displayed modest inhibitory activity against GlmS, with IC50 in the mmol L-1 range. 2010 Sociedade Brasileira de Quimica.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.COA of Formula: C9H7NO2, you can also check out more blogs about122433-29-8
Reference£º
Benzoxazole – Wikipedia,
Benzoxazole | C7H5NO – PubChem